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Anti-OTOR/ FDP/ MIAL1 functional antibody
Anti-OTOR/ FDP/ MIAL1 functional antibody for cell culture, ELISA & in-vivo assay
Go to OTOR/OTOR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0392-Ab-1/ GM-Tg-hg-SE0392-Ab-2 | Anti-Human OTOR monoclonal antibody | Human |
| GM-Tg-rg-SE0392-Ab-1/ GM-Tg-rg-SE0392-Ab-2 | Anti-Rat OTOR monoclonal antibody | Rat |
| GM-Tg-mg-SE0392-Ab-1/ GM-Tg-mg-SE0392-Ab-2 | Anti-Mouse OTOR monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0392-Ab-1/ GM-Tg-cynog-SE0392-Ab-2 | Anti-Cynomolgus/ Rhesus macaque OTOR monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0392-Ab-1/ GM-Tg-felg-SE0392-Ab-2 | Anti-Feline OTOR monoclonal antibody | Feline |
| GM-Tg-cang-SE0392-Ab-1/ GM-Tg-cang-SE0392-Ab-2 | Anti-Canine OTOR monoclonal antibody | Canine |
| GM-Tg-bovg-SE0392-Ab-1/ GM-Tg-bovg-SE0392-Ab-2 | Anti-Bovine OTOR monoclonal antibody | Bovine |
| GM-Tg-equg-SE0392-Ab-1/ GM-Tg-equg-SE0392-Ab-2 | Anti-Equine OTOR monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0392-Ab-1/ GM-Tg-hg-SE0392-Ab-2; GM-Tg-rg-SE0392-Ab-1/ GM-Tg-rg-SE0392-Ab-2; GM-Tg-mg-SE0392-Ab-1/ GM-Tg-mg-SE0392-Ab-2; GM-Tg-cynog-SE0392-Ab-1/ GM-Tg-cynog-SE0392-Ab-2; GM-Tg-felg-SE0392-Ab-1/ GM-Tg-felg-SE0392-Ab-2; GM-Tg-cang-SE0392-Ab-1/ GM-Tg-cang-SE0392-Ab-2; GM-Tg-bovg-SE0392-Ab-1/ GM-Tg-bovg-SE0392-Ab-2; GM-Tg-equg-SE0392-Ab-1/ GM-Tg-equg-SE0392-Ab-2 |
| Products Name | Anti-OTOR monoclonal antibody |
| Format | mab |
| Target Name | OTOR |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-OTOR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0392-Ag-1 | Recombinant multi-species OTOR/ FDP/ MIAL1 protein |
| ORF Viral Vector | pGMLPm004524 | mouse Otor Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004524 | mouse Otor Lentivirus particle |
Target information
| Target ID | GM-SE0392 |
| Target Name | OTOR |
| Gene ID | 56914,57329,366206,695505,100856431,101097883,613456,100062839 |
| Gene Symbol and Synonyms | CDRAP,FDP,MIA,MIAL,MIAL1,OTOR |
| Uniprot Accession | Q9NRC9 |
| Uniprot Entry Name | OTOR_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000125879 |
| Target Classification | N/A |
The target: OTOR, gene name: OTOR, also named as FDP, MIAL1. This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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