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Anti-PA2GD/ PLA2G2D/ PLA2IID functional antibody
Anti-PA2GD/ PLA2G2D/ PLA2IID functional antibody for cell culture, ELISA & in-vivo assay
Go to PLA2G2D/PLA2G2D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0411-Ab-1/ GM-Tg-hg-SE0411-Ab-2 | Anti-Human PLA2G2D monoclonal antibody | Human |
| GM-Tg-rg-SE0411-Ab-1/ GM-Tg-rg-SE0411-Ab-2 | Anti-Rat PLA2G2D monoclonal antibody | Rat |
| GM-Tg-mg-SE0411-Ab-1/ GM-Tg-mg-SE0411-Ab-2 | Anti-Mouse PLA2G2D monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0411-Ab-1/ GM-Tg-cynog-SE0411-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PLA2G2D monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0411-Ab-1/ GM-Tg-felg-SE0411-Ab-2 | Anti-Feline PLA2G2D monoclonal antibody | Feline |
| GM-Tg-cang-SE0411-Ab-1/ GM-Tg-cang-SE0411-Ab-2 | Anti-Canine PLA2G2D monoclonal antibody | Canine |
| GM-Tg-bovg-SE0411-Ab-1/ GM-Tg-bovg-SE0411-Ab-2 | Anti-Bovine PLA2G2D monoclonal antibody | Bovine |
| GM-Tg-equg-SE0411-Ab-1/ GM-Tg-equg-SE0411-Ab-2 | Anti-Equine PLA2G2D monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0411-Ab-1/ GM-Tg-hg-SE0411-Ab-2; GM-Tg-rg-SE0411-Ab-1/ GM-Tg-rg-SE0411-Ab-2; GM-Tg-mg-SE0411-Ab-1/ GM-Tg-mg-SE0411-Ab-2; GM-Tg-cynog-SE0411-Ab-1/ GM-Tg-cynog-SE0411-Ab-2; GM-Tg-felg-SE0411-Ab-1/ GM-Tg-felg-SE0411-Ab-2; GM-Tg-cang-SE0411-Ab-1/ GM-Tg-cang-SE0411-Ab-2; GM-Tg-bovg-SE0411-Ab-1/ GM-Tg-bovg-SE0411-Ab-2; GM-Tg-equg-SE0411-Ab-1/ GM-Tg-equg-SE0411-Ab-2 |
| Products Name | Anti-PLA2G2D monoclonal antibody |
| Format | mab |
| Target Name | PLA2G2D |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PLA2G2D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0411-Ag-1 | Recombinant multi-species PA2GD/ PLA2G2D/ PLA2IID protein |
Target information
| Target ID | GM-SE0411 |
| Target Name | PLA2G2D |
| Gene ID | 26279,298579,704735,101091639,100071838 |
| Gene Symbol and Synonyms | PLA2G2D,PLA2IID,sPLA2-IID,sPLA2S,SPLASH |
| Uniprot Accession | Q9UNK4 |
| Uniprot Entry Name | PA2GD_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000117215 |
| Target Classification | N/A |
The target: PLA2G2D, gene name: PLA2G2D, also named as PLA2IID, SPLASH, sPLA2-IID, sPLA2S. This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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