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Anti-PRELP/ MST161/ MSTP161 functional antibody
Anti-PRELP/ MST161/ MSTP161 functional antibody for cell culture, ELISA & in-vivo assay
Go to PRELP/PRELP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0427-Ab-1/ GM-Tg-hg-SE0427-Ab-2 | Anti-Human PRELP monoclonal antibody | Human |
| GM-Tg-rg-SE0427-Ab-1/ GM-Tg-rg-SE0427-Ab-2 | Anti-Rat PRELP monoclonal antibody | Rat |
| GM-Tg-mg-SE0427-Ab-1/ GM-Tg-mg-SE0427-Ab-2 | Anti-Mouse PRELP monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0427-Ab-1/ GM-Tg-cynog-SE0427-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRELP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0427-Ab-1/ GM-Tg-felg-SE0427-Ab-2 | Anti-Feline PRELP monoclonal antibody | Feline |
| GM-Tg-cang-SE0427-Ab-1/ GM-Tg-cang-SE0427-Ab-2 | Anti-Canine PRELP monoclonal antibody | Canine |
| GM-Tg-bovg-SE0427-Ab-1/ GM-Tg-bovg-SE0427-Ab-2 | Anti-Bovine PRELP monoclonal antibody | Bovine |
| GM-Tg-equg-SE0427-Ab-1/ GM-Tg-equg-SE0427-Ab-2 | Anti-Equine PRELP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0427-Ab-1/ GM-Tg-hg-SE0427-Ab-2; GM-Tg-rg-SE0427-Ab-1/ GM-Tg-rg-SE0427-Ab-2; GM-Tg-mg-SE0427-Ab-1/ GM-Tg-mg-SE0427-Ab-2; GM-Tg-cynog-SE0427-Ab-1/ GM-Tg-cynog-SE0427-Ab-2; GM-Tg-felg-SE0427-Ab-1/ GM-Tg-felg-SE0427-Ab-2; GM-Tg-cang-SE0427-Ab-1/ GM-Tg-cang-SE0427-Ab-2; GM-Tg-bovg-SE0427-Ab-1/ GM-Tg-bovg-SE0427-Ab-2; GM-Tg-equg-SE0427-Ab-1/ GM-Tg-equg-SE0427-Ab-2 |
| Products Name | Anti-PRELP monoclonal antibody |
| Format | mab |
| Target Name | PRELP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRELP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0427-Ag-1 | Recombinant multi-species PRELP/ MST161/ MSTP161 protein |
| ORF Viral Vector | vGMLP000609 | human PRELP Lentivirus particle |
| ORF Viral Vector | pGMLP000609 | human PRELP Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001983 | mouse Prelp Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001983 | mouse Prelp Lentivirus particle |
Target information
| Target ID | GM-SE0427 |
| Target Name | PRELP |
| Gene ID | 5549,116847,84400,702702,488561,101101284,282000,100053463 |
| Gene Symbol and Synonyms | 7330409J17Rik,MST161,MSTP161,PRELP,SLRR2A |
| Uniprot Accession | P51888,Q9EQP5,Q9GKN8 |
| Uniprot Entry Name | PRELP_HUMAN,PRELP_RAT,PRELP_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000188783 |
| Target Classification | N/A |
The target: PRELP, gene name: PRELP, also named as MST161, MSTP161, SLRR2A. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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