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Anti-GLU2B/ PRKCSH/ AGE-R2 functional antibody
Anti-GLU2B/ PRKCSH/ AGE-R2 functional antibody for cell culture, ELISA & in-vivo assay
Go to PRKCSH/PRKCSH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0429-Ab-1/ GM-Tg-hg-SE0429-Ab-2 | Anti-Human PRKCSH monoclonal antibody | Human |
| GM-Tg-rg-SE0429-Ab-1/ GM-Tg-rg-SE0429-Ab-2 | Anti-Rat PRKCSH monoclonal antibody | Rat |
| GM-Tg-mg-SE0429-Ab-1/ GM-Tg-mg-SE0429-Ab-2 | Anti-Mouse PRKCSH monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0429-Ab-1/ GM-Tg-cynog-SE0429-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRKCSH monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0429-Ab-1/ GM-Tg-felg-SE0429-Ab-2 | Anti-Feline PRKCSH monoclonal antibody | Feline |
| GM-Tg-cang-SE0429-Ab-1/ GM-Tg-cang-SE0429-Ab-2 | Anti-Canine PRKCSH monoclonal antibody | Canine |
| GM-Tg-bovg-SE0429-Ab-1/ GM-Tg-bovg-SE0429-Ab-2 | Anti-Bovine PRKCSH monoclonal antibody | Bovine |
| GM-Tg-equg-SE0429-Ab-1/ GM-Tg-equg-SE0429-Ab-2 | Anti-Equine PRKCSH monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0429-Ab-1/ GM-Tg-hg-SE0429-Ab-2; GM-Tg-rg-SE0429-Ab-1/ GM-Tg-rg-SE0429-Ab-2; GM-Tg-mg-SE0429-Ab-1/ GM-Tg-mg-SE0429-Ab-2; GM-Tg-cynog-SE0429-Ab-1/ GM-Tg-cynog-SE0429-Ab-2; GM-Tg-felg-SE0429-Ab-1/ GM-Tg-felg-SE0429-Ab-2; GM-Tg-cang-SE0429-Ab-1/ GM-Tg-cang-SE0429-Ab-2; GM-Tg-bovg-SE0429-Ab-1/ GM-Tg-bovg-SE0429-Ab-2; GM-Tg-equg-SE0429-Ab-1/ GM-Tg-equg-SE0429-Ab-2 |
| Products Name | Anti-PRKCSH monoclonal antibody |
| Format | mab |
| Target Name | PRKCSH |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRKCSH benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0429-Ag-1 | Recombinant multi-species GLU2B/ PRKCSH/ AGE-R2 protein |
Target information
| Target ID | GM-SE0429 |
| Target Name | PRKCSH |
| Gene ID | 5589,19089,300445,714650,484941,101081869,338067,100056942 |
| Gene Symbol and Synonyms | 80K-H,AGE-R2,G19P1,GIIB,PCLD,PCLD1,PKCSH,PLD1,PRKCSH,VASAP-60 |
| Uniprot Accession | P14314,Q28034 |
| Uniprot Entry Name | GLU2B_HUMAN,GLU2B_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130175 |
| Target Classification | N/A |
The target: PRKCSH, gene name: PRKCSH, also named as AGE-R2, G19P1, GIIB, PCLD, PCLD1, PKCSH, PLD1, VASAP-60. This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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