Anti-PRRP/ PRLH/ PRH functional antibody

Anti-PRRP/ PRLH/ PRH functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to PRLH/PRLH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0430-Ab-1/ GM-Tg-hg-SE0430-Ab-2Anti-Human PRLH monoclonal antibodyHuman
GM-Tg-rg-SE0430-Ab-1/ GM-Tg-rg-SE0430-Ab-2Anti-Rat PRLH monoclonal antibodyRat
GM-Tg-mg-SE0430-Ab-1/ GM-Tg-mg-SE0430-Ab-2Anti-Mouse PRLH monoclonal antibodyMouse
GM-Tg-cynog-SE0430-Ab-1/ GM-Tg-cynog-SE0430-Ab-2Anti-Cynomolgus/ Rhesus macaque PRLH monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0430-Ab-1/ GM-Tg-felg-SE0430-Ab-2Anti-Feline PRLH monoclonal antibodyFeline
GM-Tg-cang-SE0430-Ab-1/ GM-Tg-cang-SE0430-Ab-2Anti-Canine PRLH monoclonal antibodyCanine
GM-Tg-bovg-SE0430-Ab-1/ GM-Tg-bovg-SE0430-Ab-2Anti-Bovine PRLH monoclonal antibodyBovine
GM-Tg-equg-SE0430-Ab-1/ GM-Tg-equg-SE0430-Ab-2Anti-Equine PRLH monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0430-Ab-1/ GM-Tg-hg-SE0430-Ab-2; GM-Tg-rg-SE0430-Ab-1/ GM-Tg-rg-SE0430-Ab-2;
GM-Tg-mg-SE0430-Ab-1/ GM-Tg-mg-SE0430-Ab-2; GM-Tg-cynog-SE0430-Ab-1/ GM-Tg-cynog-SE0430-Ab-2;
GM-Tg-felg-SE0430-Ab-1/ GM-Tg-felg-SE0430-Ab-2; GM-Tg-cang-SE0430-Ab-1/ GM-Tg-cang-SE0430-Ab-2;
GM-Tg-bovg-SE0430-Ab-1/ GM-Tg-bovg-SE0430-Ab-2; GM-Tg-equg-SE0430-Ab-1/ GM-Tg-equg-SE0430-Ab-2
Products NameAnti-PRLH monoclonal antibody
Formatmab
Target NamePRLH
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRLH benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0430-Ag-1Recombinant multi-species PRRP/ PRLH/ PRH protein


    Target information

    Target IDGM-SE0430
    Target NamePRLH
    Gene ID51052,623503,63850,694941,111092307,102902411,286856,111773870
    Gene Symbol and SynonymsEG623503,PRH,PRLH,PRRP
    Uniprot AccessionP81277,P81278,P81264
    Uniprot Entry NamePRRP_HUMAN,PRRP_RAT,PRRP_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000071677
    Target ClassificationN/A

    The target: PRLH, gene name: PRLH, also named as PRH, PRRP. Predicted to enable neuropeptide hormone activity and prolactin-releasing peptide receptor binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway; feeding behavior; and response to peptide hormone. Predicted to act upstream of or within several processes, including energy reserve metabolic process; fat cell differentiation; and reduction of food intake in response to dietary excess. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.