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Anti-RCN3/ RLP49 functional antibody
Anti-RCN3/ RLP49 functional antibody for cell culture, ELISA & in-vivo assay
Go to RCN3/RCN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0443-Ab-1/ GM-Tg-hg-SE0443-Ab-2 | Anti-Human RCN3 monoclonal antibody | Human |
| GM-Tg-rg-SE0443-Ab-1/ GM-Tg-rg-SE0443-Ab-2 | Anti-Rat RCN3 monoclonal antibody | Rat |
| GM-Tg-mg-SE0443-Ab-1/ GM-Tg-mg-SE0443-Ab-2 | Anti-Mouse RCN3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0443-Ab-1/ GM-Tg-cynog-SE0443-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RCN3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0443-Ab-1/ GM-Tg-felg-SE0443-Ab-2 | Anti-Feline RCN3 monoclonal antibody | Feline |
| GM-Tg-cang-SE0443-Ab-1/ GM-Tg-cang-SE0443-Ab-2 | Anti-Canine RCN3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0443-Ab-1/ GM-Tg-bovg-SE0443-Ab-2 | Anti-Bovine RCN3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0443-Ab-1/ GM-Tg-equg-SE0443-Ab-2 | Anti-Equine RCN3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0443-Ab-1/ GM-Tg-hg-SE0443-Ab-2; GM-Tg-rg-SE0443-Ab-1/ GM-Tg-rg-SE0443-Ab-2; GM-Tg-mg-SE0443-Ab-1/ GM-Tg-mg-SE0443-Ab-2; GM-Tg-cynog-SE0443-Ab-1/ GM-Tg-cynog-SE0443-Ab-2; GM-Tg-felg-SE0443-Ab-1/ GM-Tg-felg-SE0443-Ab-2; GM-Tg-cang-SE0443-Ab-1/ GM-Tg-cang-SE0443-Ab-2; GM-Tg-bovg-SE0443-Ab-1/ GM-Tg-bovg-SE0443-Ab-2; GM-Tg-equg-SE0443-Ab-1/ GM-Tg-equg-SE0443-Ab-2 |
| Products Name | Anti-RCN3 monoclonal antibody |
| Format | mab |
| Target Name | RCN3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RCN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0443-Ag-1 | Recombinant multi-species RCN3/ RLP49 protein |
| ORF Viral Vector | pGMLP004117 | human RCN3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004117 | human RCN3 Lentivirus particle |
| ORF Viral Vector | pGMLPm004125 | mouse Rcn3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004125 | mouse Rcn3 Lentivirus particle |
Target information
| Target ID | GM-SE0443 |
| Target Name | RCN3 |
| Gene ID | 57333,52377,494125,719293,484379,101081269,522073,100055602 |
| Gene Symbol and Synonyms | 6030455P07Rik,D530026G20Rik,D7Ertd671e,RCN3,Rem1,RLP49 |
| Uniprot Accession | Q96D15,I6L9G5,Q2KJ39 |
| Uniprot Entry Name | RCN3_HUMAN,RCN3_RAT,RCN3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000142552 |
| Target Classification | N/A |
The target: RCN3, gene name: RCN3, also named as RLP49. Enables calcium ion binding activity. Involved in several processes, including collagen biosynthetic process; positive regulation of peptidase activity; and regulation of protein kinase B signaling. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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