Anti-RFNG functional antibody

Anti-RFNG functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to RFNG/RFNG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0444-Ab-1/ GM-Tg-hg-SE0444-Ab-2Anti-Human RFNG monoclonal antibodyHuman
GM-Tg-rg-SE0444-Ab-1/ GM-Tg-rg-SE0444-Ab-2Anti-Rat RFNG monoclonal antibodyRat
GM-Tg-mg-SE0444-Ab-1/ GM-Tg-mg-SE0444-Ab-2Anti-Mouse RFNG monoclonal antibodyMouse
GM-Tg-cynog-SE0444-Ab-1/ GM-Tg-cynog-SE0444-Ab-2Anti-Cynomolgus/ Rhesus macaque RFNG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0444-Ab-1/ GM-Tg-felg-SE0444-Ab-2Anti-Feline RFNG monoclonal antibodyFeline
GM-Tg-cang-SE0444-Ab-1/ GM-Tg-cang-SE0444-Ab-2Anti-Canine RFNG monoclonal antibodyCanine
GM-Tg-bovg-SE0444-Ab-1/ GM-Tg-bovg-SE0444-Ab-2Anti-Bovine RFNG monoclonal antibodyBovine
GM-Tg-equg-SE0444-Ab-1/ GM-Tg-equg-SE0444-Ab-2Anti-Equine RFNG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0444-Ab-1/ GM-Tg-hg-SE0444-Ab-2; GM-Tg-rg-SE0444-Ab-1/ GM-Tg-rg-SE0444-Ab-2;
GM-Tg-mg-SE0444-Ab-1/ GM-Tg-mg-SE0444-Ab-2; GM-Tg-cynog-SE0444-Ab-1/ GM-Tg-cynog-SE0444-Ab-2;
GM-Tg-felg-SE0444-Ab-1/ GM-Tg-felg-SE0444-Ab-2; GM-Tg-cang-SE0444-Ab-1/ GM-Tg-cang-SE0444-Ab-2;
GM-Tg-bovg-SE0444-Ab-1/ GM-Tg-bovg-SE0444-Ab-2; GM-Tg-equg-SE0444-Ab-1/ GM-Tg-equg-SE0444-Ab-2
Products NameAnti-RFNG monoclonal antibody
Formatmab
Target NameRFNG
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RFNG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0444-Ag-1Recombinant multi-species RFNG protein


    Target information

    Target IDGM-SE0444
    Target NameRFNG
    Gene ID5986,19719,60433,719330,483376,101080753,532242,100057395
    Gene Symbol and SynonymsRFNG
    Uniprot AccessionQ9Y644,Q9R1U9
    Uniprot Entry NameRFNG_HUMAN,RFNG_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169733
    Target ClassificationN/A

    The target: RFNG, gene name: RFNG, also named as . Predicted to enable O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Predicted to be involved in regulation of Notch signaling pathway. Predicted to act upstream of or within positive regulation of Notch signaling pathway and positive regulation of protein binding activity. Predicted to be integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.