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Anti-RTBDN functional antibody
Anti-RTBDN functional antibody for cell culture, ELISA & in-vivo assay
Go to RTBDN/RTBDN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0453-Ab-1/ GM-Tg-hg-SE0453-Ab-2 | Anti-Human RTBDN monoclonal antibody | Human |
| GM-Tg-rg-SE0453-Ab-1/ GM-Tg-rg-SE0453-Ab-2 | Anti-Rat RTBDN monoclonal antibody | Rat |
| GM-Tg-mg-SE0453-Ab-1/ GM-Tg-mg-SE0453-Ab-2 | Anti-Mouse RTBDN monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0453-Ab-1/ GM-Tg-cynog-SE0453-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RTBDN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0453-Ab-1/ GM-Tg-felg-SE0453-Ab-2 | Anti-Feline RTBDN monoclonal antibody | Feline |
| GM-Tg-cang-SE0453-Ab-1/ GM-Tg-cang-SE0453-Ab-2 | Anti-Canine RTBDN monoclonal antibody | Canine |
| GM-Tg-bovg-SE0453-Ab-1/ GM-Tg-bovg-SE0453-Ab-2 | Anti-Bovine RTBDN monoclonal antibody | Bovine |
| GM-Tg-equg-SE0453-Ab-1/ GM-Tg-equg-SE0453-Ab-2 | Anti-Equine RTBDN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0453-Ab-1/ GM-Tg-hg-SE0453-Ab-2; GM-Tg-rg-SE0453-Ab-1/ GM-Tg-rg-SE0453-Ab-2; GM-Tg-mg-SE0453-Ab-1/ GM-Tg-mg-SE0453-Ab-2; GM-Tg-cynog-SE0453-Ab-1/ GM-Tg-cynog-SE0453-Ab-2; GM-Tg-felg-SE0453-Ab-1/ GM-Tg-felg-SE0453-Ab-2; GM-Tg-cang-SE0453-Ab-1/ GM-Tg-cang-SE0453-Ab-2; GM-Tg-bovg-SE0453-Ab-1/ GM-Tg-bovg-SE0453-Ab-2; GM-Tg-equg-SE0453-Ab-1/ GM-Tg-equg-SE0453-Ab-2 |
| Products Name | Anti-RTBDN monoclonal antibody |
| Format | mab |
| Target Name | RTBDN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RTBDN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0453-Ag-1 | Recombinant multi-species RTBDN protein |
Target information
| Target ID | GM-SE0453 |
| Target Name | RTBDN |
| Gene ID | 83546,234542,304667,716766,476698,101086375,784508,100064212 |
| Gene Symbol and Synonyms | A330096I21Rik,RTBDN,Rtbnd |
| Uniprot Accession | Q9BSG5,Q4TUC0 |
| Uniprot Entry Name | RTBDN_HUMAN,RTBDN_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000132026 |
| Target Classification | N/A |
The target: RTBDN, gene name: RTBDN, also named as . This gene was first identified in a study of human eye tissues. The protein encoded by this gene is preferentially expressed in the retina and may play a role in binding retinoids and other carotenoids as it shares homology with riboflavin binding proteins. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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