Anti-SEM6C/ SEMA6C/ SEMAY functional antibody

Anti-SEM6C/ SEMA6C/ SEMAY functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SEMA6C/SEMA6C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0463-Ab-1/ GM-Tg-hg-SE0463-Ab-2Anti-Human SEMA6C monoclonal antibodyHuman
GM-Tg-rg-SE0463-Ab-1/ GM-Tg-rg-SE0463-Ab-2Anti-Rat SEMA6C monoclonal antibodyRat
GM-Tg-mg-SE0463-Ab-1/ GM-Tg-mg-SE0463-Ab-2Anti-Mouse SEMA6C monoclonal antibodyMouse
GM-Tg-cynog-SE0463-Ab-1/ GM-Tg-cynog-SE0463-Ab-2Anti-Cynomolgus/ Rhesus macaque SEMA6C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0463-Ab-1/ GM-Tg-felg-SE0463-Ab-2Anti-Feline SEMA6C monoclonal antibodyFeline
GM-Tg-cang-SE0463-Ab-1/ GM-Tg-cang-SE0463-Ab-2Anti-Canine SEMA6C monoclonal antibodyCanine
GM-Tg-bovg-SE0463-Ab-1/ GM-Tg-bovg-SE0463-Ab-2Anti-Bovine SEMA6C monoclonal antibodyBovine
GM-Tg-equg-SE0463-Ab-1/ GM-Tg-equg-SE0463-Ab-2Anti-Equine SEMA6C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0463-Ab-1/ GM-Tg-hg-SE0463-Ab-2; GM-Tg-rg-SE0463-Ab-1/ GM-Tg-rg-SE0463-Ab-2;
GM-Tg-mg-SE0463-Ab-1/ GM-Tg-mg-SE0463-Ab-2; GM-Tg-cynog-SE0463-Ab-1/ GM-Tg-cynog-SE0463-Ab-2;
GM-Tg-felg-SE0463-Ab-1/ GM-Tg-felg-SE0463-Ab-2; GM-Tg-cang-SE0463-Ab-1/ GM-Tg-cang-SE0463-Ab-2;
GM-Tg-bovg-SE0463-Ab-1/ GM-Tg-bovg-SE0463-Ab-2; GM-Tg-equg-SE0463-Ab-1/ GM-Tg-equg-SE0463-Ab-2
Products NameAnti-SEMA6C monoclonal antibody
Formatmab
Target NameSEMA6C
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SEMA6C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0463-Ag-1Recombinant multi-species SEM6C/ SEMA6C/ SEMAY protein


    Target information

    Target IDGM-SE0463
    Target NameSEMA6C
    Gene ID10500,20360,29744,709464,483191,101083785,524464,100059476
    Gene Symbol and Synonymsm-SemaY,m-SemaY2,mKIAA1869,Sema-Y,SEMA6C,SEMAY
    Uniprot AccessionQ9H3T2,Q9WTL3
    Uniprot Entry NameSEM6C_HUMAN,SEM6C_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000143434
    Target ClassificationN/A

    The target: SEMA6C, gene name: SEMA6C, also named as SEMAY, m-SemaY, m-SemaY2. This gene encodes a member of the semaphorin family. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.