Anti-SPA9/ SERPINA9/ GCET1 functional antibody

Anti-SPA9/ SERPINA9/ GCET1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SERPINA9/SERPINA9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0468-Ab-1/ GM-Tg-hg-SE0468-Ab-2Anti-Human SERPINA9 monoclonal antibodyHuman
GM-Tg-rg-SE0468-Ab-1/ GM-Tg-rg-SE0468-Ab-2Anti-Rat SERPINA9 monoclonal antibodyRat
GM-Tg-mg-SE0468-Ab-1/ GM-Tg-mg-SE0468-Ab-2Anti-Mouse SERPINA9 monoclonal antibodyMouse
GM-Tg-cynog-SE0468-Ab-1/ GM-Tg-cynog-SE0468-Ab-2Anti-Cynomolgus/ Rhesus macaque SERPINA9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0468-Ab-1/ GM-Tg-felg-SE0468-Ab-2Anti-Feline SERPINA9 monoclonal antibodyFeline
GM-Tg-cang-SE0468-Ab-1/ GM-Tg-cang-SE0468-Ab-2Anti-Canine SERPINA9 monoclonal antibodyCanine
GM-Tg-bovg-SE0468-Ab-1/ GM-Tg-bovg-SE0468-Ab-2Anti-Bovine SERPINA9 monoclonal antibodyBovine
GM-Tg-equg-SE0468-Ab-1/ GM-Tg-equg-SE0468-Ab-2Anti-Equine SERPINA9 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0468-Ab-1/ GM-Tg-hg-SE0468-Ab-2; GM-Tg-rg-SE0468-Ab-1/ GM-Tg-rg-SE0468-Ab-2;
GM-Tg-mg-SE0468-Ab-1/ GM-Tg-mg-SE0468-Ab-2; GM-Tg-cynog-SE0468-Ab-1/ GM-Tg-cynog-SE0468-Ab-2;
GM-Tg-felg-SE0468-Ab-1/ GM-Tg-felg-SE0468-Ab-2; GM-Tg-cang-SE0468-Ab-1/ GM-Tg-cang-SE0468-Ab-2;
GM-Tg-bovg-SE0468-Ab-1/ GM-Tg-bovg-SE0468-Ab-2; GM-Tg-equg-SE0468-Ab-1/ GM-Tg-equg-SE0468-Ab-2
Products NameAnti-SERPINA9 monoclonal antibody
Formatmab
Target NameSERPINA9
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SERPINA9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0468-Ag-1Recombinant multi-species SPA9/ SERPINA9/ GCET1 protein


    Target information

    Target IDGM-SE0468
    Target NameSERPINA9
    Gene ID327657,71907,707962,101081390,102150655
    Gene Symbol and Synonyms2310014L03Rik,Centerin,GCET1,SERPINA11,SERPINA11b,SERPINA9
    Uniprot AccessionQ86WD7
    Uniprot Entry NameSPA9_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000170054
    Target ClassificationN/A

    The target: SERPINA9, gene name: SERPINA9, also named as GCET1, SERPINA11, SERPINA11b. Enables serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in cytoplasm and membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.