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Anti-SMOC2/ DTDP1/ MST117 functional antibody
Anti-SMOC2/ DTDP1/ MST117 functional antibody for cell culture, ELISA & in-vivo assay
Go to SMOC2/SMOC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0478-Ab-1/ GM-Tg-hg-SE0478-Ab-2 | Anti-Human SMOC2 monoclonal antibody | Human |
| GM-Tg-rg-SE0478-Ab-1/ GM-Tg-rg-SE0478-Ab-2 | Anti-Rat SMOC2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0478-Ab-1/ GM-Tg-mg-SE0478-Ab-2 | Anti-Mouse SMOC2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0478-Ab-1/ GM-Tg-cynog-SE0478-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SMOC2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0478-Ab-1/ GM-Tg-felg-SE0478-Ab-2 | Anti-Feline SMOC2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0478-Ab-1/ GM-Tg-cang-SE0478-Ab-2 | Anti-Canine SMOC2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0478-Ab-1/ GM-Tg-bovg-SE0478-Ab-2 | Anti-Bovine SMOC2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0478-Ab-1/ GM-Tg-equg-SE0478-Ab-2 | Anti-Equine SMOC2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0478-Ab-1/ GM-Tg-hg-SE0478-Ab-2; GM-Tg-rg-SE0478-Ab-1/ GM-Tg-rg-SE0478-Ab-2; GM-Tg-mg-SE0478-Ab-1/ GM-Tg-mg-SE0478-Ab-2; GM-Tg-cynog-SE0478-Ab-1/ GM-Tg-cynog-SE0478-Ab-2; GM-Tg-felg-SE0478-Ab-1/ GM-Tg-felg-SE0478-Ab-2; GM-Tg-cang-SE0478-Ab-1/ GM-Tg-cang-SE0478-Ab-2; GM-Tg-bovg-SE0478-Ab-1/ GM-Tg-bovg-SE0478-Ab-2; GM-Tg-equg-SE0478-Ab-1/ GM-Tg-equg-SE0478-Ab-2 |
| Products Name | Anti-SMOC2 monoclonal antibody |
| Format | mab |
| Target Name | SMOC2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SMOC2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0478-Ag-1 | Recombinant multi-species SMOC2/ DTDP1/ MST117 protein |
| ORF Viral Vector | pGMLPm001619 | mouse Smoc2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001619 | mouse Smoc2 Lentivirus particle |
Target information
| Target ID | GM-SE0478 |
| Target Name | SMOC2 |
| Gene ID | 64094,64074,292401,722569,476270,101082409,615490,100054389 |
| Gene Symbol and Synonyms | 1700056C05Rik,5430426J21Rik,bA270C4A.1,bA37D8.1,dJ421D16.1,DTDP1,MST117,MSTP117,MSTP140,SMAP2,SMOC2,Smoc2l |
| Uniprot Accession | Q9H3U7 |
| Uniprot Entry Name | SMOC2_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000112562 |
| Target Classification | N/A |
The target: SMOC2, gene name: SMOC2, also named as DTDP1, MST117, MSTP117, MSTP140, SMAP2, bA270C4A.1, bA37D8.1, dJ421D16.1. This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
