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Anti-SIAT6/ ST3GAL3/ EIEE15 functional antibody
Anti-SIAT6/ ST3GAL3/ EIEE15 functional antibody for cell culture, ELISA & in-vivo assay
Go to ST3GAL3/ST3GAL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0488-Ab-1/ GM-Tg-hg-SE0488-Ab-2 | Anti-Human ST3GAL3 monoclonal antibody | Human |
| GM-Tg-rg-SE0488-Ab-1/ GM-Tg-rg-SE0488-Ab-2 | Anti-Rat ST3GAL3 monoclonal antibody | Rat |
| GM-Tg-mg-SE0488-Ab-1/ GM-Tg-mg-SE0488-Ab-2 | Anti-Mouse ST3GAL3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0488-Ab-1/ GM-Tg-cynog-SE0488-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ST3GAL3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0488-Ab-1/ GM-Tg-felg-SE0488-Ab-2 | Anti-Feline ST3GAL3 monoclonal antibody | Feline |
| GM-Tg-cang-SE0488-Ab-1/ GM-Tg-cang-SE0488-Ab-2 | Anti-Canine ST3GAL3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0488-Ab-1/ GM-Tg-bovg-SE0488-Ab-2 | Anti-Bovine ST3GAL3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0488-Ab-1/ GM-Tg-equg-SE0488-Ab-2 | Anti-Equine ST3GAL3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0488-Ab-1/ GM-Tg-hg-SE0488-Ab-2; GM-Tg-rg-SE0488-Ab-1/ GM-Tg-rg-SE0488-Ab-2; GM-Tg-mg-SE0488-Ab-1/ GM-Tg-mg-SE0488-Ab-2; GM-Tg-cynog-SE0488-Ab-1/ GM-Tg-cynog-SE0488-Ab-2; GM-Tg-felg-SE0488-Ab-1/ GM-Tg-felg-SE0488-Ab-2; GM-Tg-cang-SE0488-Ab-1/ GM-Tg-cang-SE0488-Ab-2; GM-Tg-bovg-SE0488-Ab-1/ GM-Tg-bovg-SE0488-Ab-2; GM-Tg-equg-SE0488-Ab-1/ GM-Tg-equg-SE0488-Ab-2 |
| Products Name | Anti-ST3GAL3 monoclonal antibody |
| Format | mab |
| Target Name | ST3GAL3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ST3GAL3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0488-Ag-1 | Recombinant multi-species SIAT6/ ST3GAL3/ EIEE15 protein |
Target information
| Target ID | GM-SE0488 |
| Target Name | ST3GAL3 |
| Gene ID | 6487,20441,64445,703599,610736,101081911,444859,100053104 |
| Gene Symbol and Synonyms | DEE15,EIEE15,MRT12,Siat3,SIAT6,ST3Gal III,ST3GAL3,ST3GALII,ST3GalIII,ST3N |
| Uniprot Accession | Q11203,Q02734 |
| Uniprot Entry Name | SIAT6_HUMAN,SIAT6_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000126091 |
| Target Classification | N/A |
The target: ST3GAL3, gene name: ST3GAL3, also named as EIEE15, MRT12, SIAT6, ST3GALII, ST3Gal III, ST3GalIII, ST3N. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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