Anti-TECT3/ TCTN3/ C10orf61 functional antibody

Anti-TECT3/ TCTN3/ C10orf61 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TCTN3/TCTN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0497-Ab-1/ GM-Tg-hg-SE0497-Ab-2Anti-Human TCTN3 monoclonal antibodyHuman
GM-Tg-rg-SE0497-Ab-1/ GM-Tg-rg-SE0497-Ab-2Anti-Rat TCTN3 monoclonal antibodyRat
GM-Tg-mg-SE0497-Ab-1/ GM-Tg-mg-SE0497-Ab-2Anti-Mouse TCTN3 monoclonal antibodyMouse
GM-Tg-cynog-SE0497-Ab-1/ GM-Tg-cynog-SE0497-Ab-2Anti-Cynomolgus/ Rhesus macaque TCTN3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0497-Ab-1/ GM-Tg-felg-SE0497-Ab-2Anti-Feline TCTN3 monoclonal antibodyFeline
GM-Tg-cang-SE0497-Ab-1/ GM-Tg-cang-SE0497-Ab-2Anti-Canine TCTN3 monoclonal antibodyCanine
GM-Tg-bovg-SE0497-Ab-1/ GM-Tg-bovg-SE0497-Ab-2Anti-Bovine TCTN3 monoclonal antibodyBovine
GM-Tg-equg-SE0497-Ab-1/ GM-Tg-equg-SE0497-Ab-2Anti-Equine TCTN3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0497-Ab-1/ GM-Tg-hg-SE0497-Ab-2; GM-Tg-rg-SE0497-Ab-1/ GM-Tg-rg-SE0497-Ab-2;
GM-Tg-mg-SE0497-Ab-1/ GM-Tg-mg-SE0497-Ab-2; GM-Tg-cynog-SE0497-Ab-1/ GM-Tg-cynog-SE0497-Ab-2;
GM-Tg-felg-SE0497-Ab-1/ GM-Tg-felg-SE0497-Ab-2; GM-Tg-cang-SE0497-Ab-1/ GM-Tg-cang-SE0497-Ab-2;
GM-Tg-bovg-SE0497-Ab-1/ GM-Tg-bovg-SE0497-Ab-2; GM-Tg-equg-SE0497-Ab-1/ GM-Tg-equg-SE0497-Ab-2
Products NameAnti-TCTN3 monoclonal antibody
Formatmab
Target NameTCTN3
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TCTN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0497-Ag-1Recombinant multi-species TECT3/ TCTN3/ C10orf61 protein


    Target information

    Target IDGM-SE0497
    Target NameTCTN3
    Gene ID26123,67590,309486,703844,608523,101096108,511035,100070964
    Gene Symbol and Synonyms4930521E07Rik,C10orf61,JBTS18,OFD4,RGD1305166,TCTN3,TECT3
    Uniprot AccessionQ6NUS6
    Uniprot Entry NameTECT3_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000119977
    Target ClassificationN/A

    The target: TCTN3, gene name: TCTN3, also named as C10orf61, JBTS18, OFD4, TECT3. This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.