Anti-TLL2 functional antibody

Anti-TLL2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TLL2/TLL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0508-Ab-1/ GM-Tg-hg-SE0508-Ab-2Anti-Human TLL2 monoclonal antibodyHuman
GM-Tg-rg-SE0508-Ab-1/ GM-Tg-rg-SE0508-Ab-2Anti-Rat TLL2 monoclonal antibodyRat
GM-Tg-mg-SE0508-Ab-1/ GM-Tg-mg-SE0508-Ab-2Anti-Mouse TLL2 monoclonal antibodyMouse
GM-Tg-cynog-SE0508-Ab-1/ GM-Tg-cynog-SE0508-Ab-2Anti-Cynomolgus/ Rhesus macaque TLL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0508-Ab-1/ GM-Tg-felg-SE0508-Ab-2Anti-Feline TLL2 monoclonal antibodyFeline
GM-Tg-cang-SE0508-Ab-1/ GM-Tg-cang-SE0508-Ab-2Anti-Canine TLL2 monoclonal antibodyCanine
GM-Tg-bovg-SE0508-Ab-1/ GM-Tg-bovg-SE0508-Ab-2Anti-Bovine TLL2 monoclonal antibodyBovine
GM-Tg-equg-SE0508-Ab-1/ GM-Tg-equg-SE0508-Ab-2Anti-Equine TLL2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0508-Ab-1/ GM-Tg-hg-SE0508-Ab-2; GM-Tg-rg-SE0508-Ab-1/ GM-Tg-rg-SE0508-Ab-2;
GM-Tg-mg-SE0508-Ab-1/ GM-Tg-mg-SE0508-Ab-2; GM-Tg-cynog-SE0508-Ab-1/ GM-Tg-cynog-SE0508-Ab-2;
GM-Tg-felg-SE0508-Ab-1/ GM-Tg-felg-SE0508-Ab-2; GM-Tg-cang-SE0508-Ab-1/ GM-Tg-cang-SE0508-Ab-2;
GM-Tg-bovg-SE0508-Ab-1/ GM-Tg-bovg-SE0508-Ab-2; GM-Tg-equg-SE0508-Ab-1/ GM-Tg-equg-SE0508-Ab-2
Products NameAnti-TLL2 monoclonal antibody
Formatmab
Target NameTLL2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TLL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0508-Ag-1Recombinant multi-species TLL2 protein


    Target information

    Target IDGM-SE0508
    Target NameTLL2
    Gene ID7093,24087,365460,705290,486816,101086678,504975,100070823
    Gene Symbol and SynonymsRGD1559756,TLL2,Tll2b
    Uniprot AccessionQ9Y6L7
    Uniprot Entry NameTLL2_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000095587
    Target ClassificationN/A

    The target: TLL2, gene name: TLL2, also named as . This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin..



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.