Anti-™M95/ ™EM95/ UNQ9390 functional antibody

Anti-™M95/ ™EM95/ UNQ9390 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ™EM95/™EM95 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0515-Ab-1/ GM-Tg-hg-SE0515-Ab-2Anti-Human ™EM95 monoclonal antibodyHuman
GM-Tg-rg-SE0515-Ab-1/ GM-Tg-rg-SE0515-Ab-2Anti-Rat ™EM95 monoclonal antibodyRat
GM-Tg-mg-SE0515-Ab-1/ GM-Tg-mg-SE0515-Ab-2Anti-Mouse ™EM95 monoclonal antibodyMouse
GM-Tg-cynog-SE0515-Ab-1/ GM-Tg-cynog-SE0515-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM95 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0515-Ab-1/ GM-Tg-felg-SE0515-Ab-2Anti-Feline ™EM95 monoclonal antibodyFeline
GM-Tg-cang-SE0515-Ab-1/ GM-Tg-cang-SE0515-Ab-2Anti-Canine ™EM95 monoclonal antibodyCanine
GM-Tg-bovg-SE0515-Ab-1/ GM-Tg-bovg-SE0515-Ab-2Anti-Bovine ™EM95 monoclonal antibodyBovine
GM-Tg-equg-SE0515-Ab-1/ GM-Tg-equg-SE0515-Ab-2Anti-Equine ™EM95 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0515-Ab-1/ GM-Tg-hg-SE0515-Ab-2; GM-Tg-rg-SE0515-Ab-1/ GM-Tg-rg-SE0515-Ab-2;
GM-Tg-mg-SE0515-Ab-1/ GM-Tg-mg-SE0515-Ab-2; GM-Tg-cynog-SE0515-Ab-1/ GM-Tg-cynog-SE0515-Ab-2;
GM-Tg-felg-SE0515-Ab-1/ GM-Tg-felg-SE0515-Ab-2; GM-Tg-cang-SE0515-Ab-1/ GM-Tg-cang-SE0515-Ab-2;
GM-Tg-bovg-SE0515-Ab-1/ GM-Tg-bovg-SE0515-Ab-2; GM-Tg-equg-SE0515-Ab-1/ GM-Tg-equg-SE0515-Ab-2
Products NameAnti-™EM95 monoclonal antibody
Formatmab
Target Name™EM95
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™EM95 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0515-Ag-1Recombinant multi-species ™M95/ ™EM95/ UNQ9390 protein


    Target information

    Target IDGM-SE0515
    Target Name™EM95
    Gene ID339168,100503361,691982,715129,607773,101097028,614631,100072976
    Gene Symbol and Synonyms432576,™EM95,UNQ9390
    Uniprot AccessionQ3KNT9,A0A3Q1LRJ2
    Uniprot Entry Name™M95_HUMAN,™M95_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000182896
    Target ClassificationN/A

    The target: ™EM95, gene name: ™EM95, also named as UNQ9390. Predicted to be involved in fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to be located in sperm plasma membrane. Predicted to be integral component of membrane. Predicted to be active in acrosomal membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.