Anti-™11F/ ™PRSS11F functional antibody

Anti-™11F/ ™PRSS11F functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ™PRSS11F/™PRSS11F products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0517-Ab-1/ GM-Tg-hg-SE0517-Ab-2Anti-Human ™PRSS11F monoclonal antibodyHuman
GM-Tg-rg-SE0517-Ab-1/ GM-Tg-rg-SE0517-Ab-2Anti-Rat ™PRSS11F monoclonal antibodyRat
GM-Tg-mg-SE0517-Ab-1/ GM-Tg-mg-SE0517-Ab-2Anti-Mouse ™PRSS11F monoclonal antibodyMouse
GM-Tg-cynog-SE0517-Ab-1/ GM-Tg-cynog-SE0517-Ab-2Anti-Cynomolgus/ Rhesus macaque ™PRSS11F monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0517-Ab-1/ GM-Tg-felg-SE0517-Ab-2Anti-Feline ™PRSS11F monoclonal antibodyFeline
GM-Tg-cang-SE0517-Ab-1/ GM-Tg-cang-SE0517-Ab-2Anti-Canine ™PRSS11F monoclonal antibodyCanine
GM-Tg-bovg-SE0517-Ab-1/ GM-Tg-bovg-SE0517-Ab-2Anti-Bovine ™PRSS11F monoclonal antibodyBovine
GM-Tg-equg-SE0517-Ab-1/ GM-Tg-equg-SE0517-Ab-2Anti-Equine ™PRSS11F monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0517-Ab-1/ GM-Tg-hg-SE0517-Ab-2; GM-Tg-rg-SE0517-Ab-1/ GM-Tg-rg-SE0517-Ab-2;
GM-Tg-mg-SE0517-Ab-1/ GM-Tg-mg-SE0517-Ab-2; GM-Tg-cynog-SE0517-Ab-1/ GM-Tg-cynog-SE0517-Ab-2;
GM-Tg-felg-SE0517-Ab-1/ GM-Tg-felg-SE0517-Ab-2; GM-Tg-cang-SE0517-Ab-1/ GM-Tg-cang-SE0517-Ab-2;
GM-Tg-bovg-SE0517-Ab-1/ GM-Tg-bovg-SE0517-Ab-2; GM-Tg-equg-SE0517-Ab-1/ GM-Tg-equg-SE0517-Ab-2
Products NameAnti-™PRSS11F monoclonal antibody
Formatmab
Target Name™PRSS11F
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™PRSS11F benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0517-Ag-1Recombinant multi-species ™11F/ ™PRSS11F protein


    Target information

    Target IDGM-SE0517
    Target Name™PRSS11F
    Gene ID389208,498345,710088,785556
    Gene Symbol and SynonymsHATL4,RGD1560675,™PRSS11F
    Uniprot AccessionQ6ZWK6
    Uniprot Entry Name™11F_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198092
    Target ClassificationN/A

    The target: ™PRSS11F, gene name: ™PRSS11F, also named as . Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within regulation of water loss via skin. Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.