Anti-TOR3A/ ADIR/ ADIR2 functional antibody

Anti-TOR3A/ ADIR/ ADIR2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to TOR3A/TOR3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0523-Ab-1/ GM-Tg-hg-SE0523-Ab-2Anti-Human TOR3A monoclonal antibodyHuman
GM-Tg-rg-SE0523-Ab-1/ GM-Tg-rg-SE0523-Ab-2Anti-Rat TOR3A monoclonal antibodyRat
GM-Tg-mg-SE0523-Ab-1/ GM-Tg-mg-SE0523-Ab-2Anti-Mouse TOR3A monoclonal antibodyMouse
GM-Tg-cynog-SE0523-Ab-1/ GM-Tg-cynog-SE0523-Ab-2Anti-Cynomolgus/ Rhesus macaque TOR3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0523-Ab-1/ GM-Tg-felg-SE0523-Ab-2Anti-Feline TOR3A monoclonal antibodyFeline
GM-Tg-cang-SE0523-Ab-1/ GM-Tg-cang-SE0523-Ab-2Anti-Canine TOR3A monoclonal antibodyCanine
GM-Tg-bovg-SE0523-Ab-1/ GM-Tg-bovg-SE0523-Ab-2Anti-Bovine TOR3A monoclonal antibodyBovine
GM-Tg-equg-SE0523-Ab-1/ GM-Tg-equg-SE0523-Ab-2Anti-Equine TOR3A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0523-Ab-1/ GM-Tg-hg-SE0523-Ab-2; GM-Tg-rg-SE0523-Ab-1/ GM-Tg-rg-SE0523-Ab-2;
GM-Tg-mg-SE0523-Ab-1/ GM-Tg-mg-SE0523-Ab-2; GM-Tg-cynog-SE0523-Ab-1/ GM-Tg-cynog-SE0523-Ab-2;
GM-Tg-felg-SE0523-Ab-1/ GM-Tg-felg-SE0523-Ab-2; GM-Tg-cang-SE0523-Ab-1/ GM-Tg-cang-SE0523-Ab-2;
GM-Tg-bovg-SE0523-Ab-1/ GM-Tg-bovg-SE0523-Ab-2; GM-Tg-equg-SE0523-Ab-1/ GM-Tg-equg-SE0523-Ab-2
Products NameAnti-TOR3A monoclonal antibody
Formatmab
Target NameTOR3A
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-TOR3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0523-Ag-1Recombinant multi-species TOR3A/ ADIR/ ADIR2 protein


    Target information

    Target IDGM-SE0523
    Target NameTOR3A
    Gene ID64222,30935,304884,717100,490326,101084414,789634,100063083
    Gene Symbol and SynonymsADIR,ADIR2,TOR3A
    Uniprot AccessionQ9H497,Q5M936
    Uniprot Entry NameTOR3A_HUMAN,TOR3A_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000186283
    Target ClassificationN/A

    The target: TOR3A, gene name: TOR3A, also named as ADIR, ADIR2. Predicted to enable ATP binding activity. Located in endoplasmic reticulum lumen. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.