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Anti-TBB5/ TUBB/ CDCBM6 functional antibody
Anti-TBB5/ TUBB/ CDCBM6 functional antibody for cell culture, ELISA & in-vivo assay
Go to TUBB/TUBB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0529-Ab-1/ GM-Tg-hg-SE0529-Ab-2 | Anti-Human TUBB monoclonal antibody | Human |
| GM-Tg-rg-SE0529-Ab-1/ GM-Tg-rg-SE0529-Ab-2 | Anti-Rat TUBB monoclonal antibody | Rat |
| GM-Tg-mg-SE0529-Ab-1/ GM-Tg-mg-SE0529-Ab-2 | Anti-Mouse TUBB monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0529-Ab-1/ GM-Tg-cynog-SE0529-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TUBB monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0529-Ab-1/ GM-Tg-felg-SE0529-Ab-2 | Anti-Feline TUBB monoclonal antibody | Feline |
| GM-Tg-cang-SE0529-Ab-1/ GM-Tg-cang-SE0529-Ab-2 | Anti-Canine TUBB monoclonal antibody | Canine |
| GM-Tg-bovg-SE0529-Ab-1/ GM-Tg-bovg-SE0529-Ab-2 | Anti-Bovine TUBB monoclonal antibody | Bovine |
| GM-Tg-equg-SE0529-Ab-1/ GM-Tg-equg-SE0529-Ab-2 | Anti-Equine TUBB monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0529-Ab-1/ GM-Tg-hg-SE0529-Ab-2; GM-Tg-rg-SE0529-Ab-1/ GM-Tg-rg-SE0529-Ab-2; GM-Tg-mg-SE0529-Ab-1/ GM-Tg-mg-SE0529-Ab-2; GM-Tg-cynog-SE0529-Ab-1/ GM-Tg-cynog-SE0529-Ab-2; GM-Tg-felg-SE0529-Ab-1/ GM-Tg-felg-SE0529-Ab-2; GM-Tg-cang-SE0529-Ab-1/ GM-Tg-cang-SE0529-Ab-2; GM-Tg-bovg-SE0529-Ab-1/ GM-Tg-bovg-SE0529-Ab-2; GM-Tg-equg-SE0529-Ab-1/ GM-Tg-equg-SE0529-Ab-2 |
| Products Name | Anti-TUBB monoclonal antibody |
| Format | mab |
| Target Name | TUBB |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TUBB benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0529-Ag-1 | Recombinant multi-species TBB5/ TUBB/ CDCBM6 protein |
| ORF Viral Vector | vGMLP000488 | human TUBB Lentivirus particle |
| ORF Viral Vector | pGMLP000488 | human TUBB Lentivirus plasmid |
| ORF Viral Vector | vGMAP000420 | Human TUBB Adenovirus particle |
| ORF Viral Vector | pGMAP000420 | Human TUBB Adenovirus plasmid |
Target information
| Target ID | GM-SE0529 |
| Target Name | TUBB |
| Gene ID | 203068,22154,29214,574113,474830,101095657,615087,100051013 |
| Gene Symbol and Synonyms | B130022C14Rik,CDCBM6,CSCSC1,M(beta)5,M40,OK/SW-cl.56,TUBB,TUBB1,TUBB2A,TUBB2B,TUBB5 |
| Uniprot Accession | P07437,P69897,P69895,Q2KJD0 |
| Uniprot Entry Name | TBB5_HUMAN,TBB5_MACMU,TBB5_RAT,TBB5_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000196230 |
| Target Classification | N/A |
The target: TUBB, gene name: TUBB, also named as CDCBM6, CSCSC1, M40, OK/SW-cl.561, TUBB5, TUBB. This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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