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Anti-UDB28/ UGT2B28 functional antibody
Anti-UDB28/ UGT2B28 functional antibody for cell culture, ELISA & in-vivo assay
Go to UGT2B28/UGT2B28 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0536-Ab-1/ GM-Tg-hg-SE0536-Ab-2 | Anti-Human UGT2B28 monoclonal antibody | Human |
| GM-Tg-rg-SE0536-Ab-1/ GM-Tg-rg-SE0536-Ab-2 | Anti-Rat UGT2B28 monoclonal antibody | Rat |
| GM-Tg-mg-SE0536-Ab-1/ GM-Tg-mg-SE0536-Ab-2 | Anti-Mouse UGT2B28 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0536-Ab-1/ GM-Tg-cynog-SE0536-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UGT2B28 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0536-Ab-1/ GM-Tg-felg-SE0536-Ab-2 | Anti-Feline UGT2B28 monoclonal antibody | Feline |
| GM-Tg-cang-SE0536-Ab-1/ GM-Tg-cang-SE0536-Ab-2 | Anti-Canine UGT2B28 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0536-Ab-1/ GM-Tg-bovg-SE0536-Ab-2 | Anti-Bovine UGT2B28 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0536-Ab-1/ GM-Tg-equg-SE0536-Ab-2 | Anti-Equine UGT2B28 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0536-Ab-1/ GM-Tg-hg-SE0536-Ab-2; GM-Tg-rg-SE0536-Ab-1/ GM-Tg-rg-SE0536-Ab-2; GM-Tg-mg-SE0536-Ab-1/ GM-Tg-mg-SE0536-Ab-2; GM-Tg-cynog-SE0536-Ab-1/ GM-Tg-cynog-SE0536-Ab-2; GM-Tg-felg-SE0536-Ab-1/ GM-Tg-felg-SE0536-Ab-2; GM-Tg-cang-SE0536-Ab-1/ GM-Tg-cang-SE0536-Ab-2; GM-Tg-bovg-SE0536-Ab-1/ GM-Tg-bovg-SE0536-Ab-2; GM-Tg-equg-SE0536-Ab-1/ GM-Tg-equg-SE0536-Ab-2 |
| Products Name | Anti-UGT2B28 monoclonal antibody |
| Format | mab |
| Target Name | UGT2B28 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UGT2B28 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0536-Ag-1 | Recombinant multi-species UDB28/ UGT2B28 protein |
Target information
| Target ID | GM-SE0536 |
| Target Name | UGT2B28 |
| Gene ID | 54490 |
| Gene Symbol and Synonyms | UGT2B28 |
| Uniprot Accession | Q9BY64 |
| Uniprot Entry Name | UDB28_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135226 |
| Target Classification | N/A |
The target: UGT2B28, gene name: UGT2B28, also named as . This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Two transcript variants encoding different isoforms have been found for this gene. While both isoforms are targeted to the endoplasmic reticulum, only the longer isoform appears to be active. [provided by RefSeq, May 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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