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Anti-WF10B/ WFDC10B/ WAP12 functional antibody
Anti-WF10B/ WFDC10B/ WAP12 functional antibody for cell culture, ELISA & in-vivo assay
Go to WFDC10B/WFDC10B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0550-Ab-1/ GM-Tg-hg-SE0550-Ab-2 | Anti-Human WFDC10B monoclonal antibody | Human |
| GM-Tg-rg-SE0550-Ab-1/ GM-Tg-rg-SE0550-Ab-2 | Anti-Rat WFDC10B monoclonal antibody | Rat |
| GM-Tg-mg-SE0550-Ab-1/ GM-Tg-mg-SE0550-Ab-2 | Anti-Mouse WFDC10B monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0550-Ab-1/ GM-Tg-cynog-SE0550-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WFDC10B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0550-Ab-1/ GM-Tg-felg-SE0550-Ab-2 | Anti-Feline WFDC10B monoclonal antibody | Feline |
| GM-Tg-cang-SE0550-Ab-1/ GM-Tg-cang-SE0550-Ab-2 | Anti-Canine WFDC10B monoclonal antibody | Canine |
| GM-Tg-bovg-SE0550-Ab-1/ GM-Tg-bovg-SE0550-Ab-2 | Anti-Bovine WFDC10B monoclonal antibody | Bovine |
| GM-Tg-equg-SE0550-Ab-1/ GM-Tg-equg-SE0550-Ab-2 | Anti-Equine WFDC10B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0550-Ab-1/ GM-Tg-hg-SE0550-Ab-2; GM-Tg-rg-SE0550-Ab-1/ GM-Tg-rg-SE0550-Ab-2; GM-Tg-mg-SE0550-Ab-1/ GM-Tg-mg-SE0550-Ab-2; GM-Tg-cynog-SE0550-Ab-1/ GM-Tg-cynog-SE0550-Ab-2; GM-Tg-felg-SE0550-Ab-1/ GM-Tg-felg-SE0550-Ab-2; GM-Tg-cang-SE0550-Ab-1/ GM-Tg-cang-SE0550-Ab-2; GM-Tg-bovg-SE0550-Ab-1/ GM-Tg-bovg-SE0550-Ab-2; GM-Tg-equg-SE0550-Ab-1/ GM-Tg-equg-SE0550-Ab-2 |
| Products Name | Anti-WFDC10B monoclonal antibody |
| Format | mab |
| Target Name | WFDC10B |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WFDC10B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0550-Ag-1 | Recombinant multi-species WF10B/ WFDC10B/ WAP12 protein |
Target information
| Target ID | GM-SE0550 |
| Target Name | WFDC10B |
| Gene ID | 280664,100423519 |
| Gene Symbol and Synonyms | WAP12,WFDC10B |
| Uniprot Accession | Q8IUB3 |
| Uniprot Entry Name | WF10B_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000182931 |
| Target Classification | N/A |
The target: WFDC10B, gene name: WFDC10B, also named as WAP12. This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode distinct isoforms. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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