Anti-WNT9A/ WNT14 functional antibody

Anti-WNT9A/ WNT14 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to WNT9A/WNT9A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0559-Ab-1/ GM-Tg-hg-SE0559-Ab-2Anti-Human WNT9A monoclonal antibodyHuman
GM-Tg-rg-SE0559-Ab-1/ GM-Tg-rg-SE0559-Ab-2Anti-Rat WNT9A monoclonal antibodyRat
GM-Tg-mg-SE0559-Ab-1/ GM-Tg-mg-SE0559-Ab-2Anti-Mouse WNT9A monoclonal antibodyMouse
GM-Tg-cynog-SE0559-Ab-1/ GM-Tg-cynog-SE0559-Ab-2Anti-Cynomolgus/ Rhesus macaque WNT9A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0559-Ab-1/ GM-Tg-felg-SE0559-Ab-2Anti-Feline WNT9A monoclonal antibodyFeline
GM-Tg-cang-SE0559-Ab-1/ GM-Tg-cang-SE0559-Ab-2Anti-Canine WNT9A monoclonal antibodyCanine
GM-Tg-bovg-SE0559-Ab-1/ GM-Tg-bovg-SE0559-Ab-2Anti-Bovine WNT9A monoclonal antibodyBovine
GM-Tg-equg-SE0559-Ab-1/ GM-Tg-equg-SE0559-Ab-2Anti-Equine WNT9A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0559-Ab-1/ GM-Tg-hg-SE0559-Ab-2; GM-Tg-rg-SE0559-Ab-1/ GM-Tg-rg-SE0559-Ab-2;
GM-Tg-mg-SE0559-Ab-1/ GM-Tg-mg-SE0559-Ab-2; GM-Tg-cynog-SE0559-Ab-1/ GM-Tg-cynog-SE0559-Ab-2;
GM-Tg-felg-SE0559-Ab-1/ GM-Tg-felg-SE0559-Ab-2; GM-Tg-cang-SE0559-Ab-1/ GM-Tg-cang-SE0559-Ab-2;
GM-Tg-bovg-SE0559-Ab-1/ GM-Tg-bovg-SE0559-Ab-2; GM-Tg-equg-SE0559-Ab-1/ GM-Tg-equg-SE0559-Ab-2
Products NameAnti-WNT9A monoclonal antibody
Formatmab
Target NameWNT9A
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-WNT9A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0559-Ag-1Recombinant multi-species WNT9A/ WNT14 protein
    CytokineGM-Tg-g-SE0559-Ag-1wingless-type MMTV integration site family, member 9A (WNT9A) protein


    Target information

    Target IDGM-SE0559
    Target NameWNT9A
    Gene ID7483,216795,287357,696326,482209,111560436,511308,100061110
    Gene Symbol and Synonymswnt-14,WNT14,WNT9A
    Uniprot AccessionO14904
    Uniprot Entry NameWNT9A_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000143816
    Target ClassificationN/A

    The target: WNT9A, gene name: WNT9A, also named as WNT14. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.