Anti-ZPBP1/ ZPBP functional antibody

Anti-ZPBP1/ ZPBP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ZPBP/ZPBP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0567-Ab-1/ GM-Tg-hg-SE0567-Ab-2Anti-Human ZPBP monoclonal antibodyHuman
GM-Tg-rg-SE0567-Ab-1/ GM-Tg-rg-SE0567-Ab-2Anti-Rat ZPBP monoclonal antibodyRat
GM-Tg-mg-SE0567-Ab-1/ GM-Tg-mg-SE0567-Ab-2Anti-Mouse ZPBP monoclonal antibodyMouse
GM-Tg-cynog-SE0567-Ab-1/ GM-Tg-cynog-SE0567-Ab-2Anti-Cynomolgus/ Rhesus macaque ZPBP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0567-Ab-1/ GM-Tg-felg-SE0567-Ab-2Anti-Feline ZPBP monoclonal antibodyFeline
GM-Tg-cang-SE0567-Ab-1/ GM-Tg-cang-SE0567-Ab-2Anti-Canine ZPBP monoclonal antibodyCanine
GM-Tg-bovg-SE0567-Ab-1/ GM-Tg-bovg-SE0567-Ab-2Anti-Bovine ZPBP monoclonal antibodyBovine
GM-Tg-equg-SE0567-Ab-1/ GM-Tg-equg-SE0567-Ab-2Anti-Equine ZPBP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0567-Ab-1/ GM-Tg-hg-SE0567-Ab-2; GM-Tg-rg-SE0567-Ab-1/ GM-Tg-rg-SE0567-Ab-2;
GM-Tg-mg-SE0567-Ab-1/ GM-Tg-mg-SE0567-Ab-2; GM-Tg-cynog-SE0567-Ab-1/ GM-Tg-cynog-SE0567-Ab-2;
GM-Tg-felg-SE0567-Ab-1/ GM-Tg-felg-SE0567-Ab-2; GM-Tg-cang-SE0567-Ab-1/ GM-Tg-cang-SE0567-Ab-2;
GM-Tg-bovg-SE0567-Ab-1/ GM-Tg-bovg-SE0567-Ab-2; GM-Tg-equg-SE0567-Ab-1/ GM-Tg-equg-SE0567-Ab-2
Products NameAnti-ZPBP monoclonal antibody
Formatmab
Target NameZPBP
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ZPBP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0567-Ag-1Recombinant multi-species ZPBP1/ ZPBP protein
    ORF Viral VectorvGMLP003074human ZPBP Lentivirus particle
    ORF Viral VectorpGMLP003074human ZPBP Lentivirus plasmid


    Target information

    Target IDGM-SE0567
    Target NameZPBP
    Gene ID11055,53604,498415,694335,607557,101085189,654401,100066637
    Gene Symbol and Synonyms4930486K01Rik,Iam38,Sp38,SPGF66,ZPBP,ZPBP1
    Uniprot AccessionQ9BS86
    Uniprot Entry NameZPBP1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000042813
    Target ClassificationN/A

    The target: ZPBP, gene name: ZPBP, also named as ZPBP1. ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.