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Anti-ARPC5/ ARC16/ dJ127C7.3 functional antibody
Anti-ARPC5/ ARC16/ dJ127C7.3 functional antibody for cell culture, ELISA & in-vivo assay
Go to ARPC5/ARPC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0572-Ab-1/ GM-Tg-hg-SE0572-Ab-2 | Anti-Human ARPC5 monoclonal antibody | Human |
| GM-Tg-rg-SE0572-Ab-1/ GM-Tg-rg-SE0572-Ab-2 | Anti-Rat ARPC5 monoclonal antibody | Rat |
| GM-Tg-mg-SE0572-Ab-1/ GM-Tg-mg-SE0572-Ab-2 | Anti-Mouse ARPC5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0572-Ab-1/ GM-Tg-cynog-SE0572-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ARPC5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0572-Ab-1/ GM-Tg-felg-SE0572-Ab-2 | Anti-Feline ARPC5 monoclonal antibody | Feline |
| GM-Tg-cang-SE0572-Ab-1/ GM-Tg-cang-SE0572-Ab-2 | Anti-Canine ARPC5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0572-Ab-1/ GM-Tg-bovg-SE0572-Ab-2 | Anti-Bovine ARPC5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0572-Ab-1/ GM-Tg-equg-SE0572-Ab-2 | Anti-Equine ARPC5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0572-Ab-1/ GM-Tg-hg-SE0572-Ab-2; GM-Tg-rg-SE0572-Ab-1/ GM-Tg-rg-SE0572-Ab-2; GM-Tg-mg-SE0572-Ab-1/ GM-Tg-mg-SE0572-Ab-2; GM-Tg-cynog-SE0572-Ab-1/ GM-Tg-cynog-SE0572-Ab-2; GM-Tg-felg-SE0572-Ab-1/ GM-Tg-felg-SE0572-Ab-2; GM-Tg-cang-SE0572-Ab-1/ GM-Tg-cang-SE0572-Ab-2; GM-Tg-bovg-SE0572-Ab-1/ GM-Tg-bovg-SE0572-Ab-2; GM-Tg-equg-SE0572-Ab-1/ GM-Tg-equg-SE0572-Ab-2 |
| Products Name | Anti-ARPC5 monoclonal antibody |
| Format | mab |
| Target Name | ARPC5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ARPC5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0572-Ag-1 | Recombinant multi-species ARPC5/ ARC16/ dJ127C7.3 protein |
| ORF Viral Vector | pGMLP002564 | human ARPC5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002564 | 0 ARPC5 Lentivirus particle |
| ORF Viral Vector | pGMLPm002213 | mouse Arpc5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002213 | mouse Arpc5 Lentivirus particle |
Target information
| Target ID | GM-SE0572 |
| Target Name | ARPC5 |
| Gene ID | 10092,67771,360854,714896,480037,101088207,614345,100051848 |
| Gene Symbol and Synonyms | 5830443F10Rik,ARC16,ARPC5,dJ127C7.3,p16-Arc |
| Uniprot Accession | O15511,Q4KLF8,Q3SYX9 |
| Uniprot Entry Name | ARPC5_HUMAN,ARPC5_RAT,ARPC5_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000162704 |
| Target Classification | N/A |
The target: ARPC5, gene name: ARPC5, also named as ARC16, dJ127C7.3, p16-Arc. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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