Anti-DAW1/ ODA16/ WDR69 functional antibody

Anti-DAW1/ ODA16/ WDR69 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to DAW1/DAW1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0582-Ab-1/ GM-Tg-hg-SE0582-Ab-2Anti-Human DAW1 monoclonal antibodyHuman
GM-Tg-rg-SE0582-Ab-1/ GM-Tg-rg-SE0582-Ab-2Anti-Rat DAW1 monoclonal antibodyRat
GM-Tg-mg-SE0582-Ab-1/ GM-Tg-mg-SE0582-Ab-2Anti-Mouse DAW1 monoclonal antibodyMouse
GM-Tg-cynog-SE0582-Ab-1/ GM-Tg-cynog-SE0582-Ab-2Anti-Cynomolgus/ Rhesus macaque DAW1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0582-Ab-1/ GM-Tg-felg-SE0582-Ab-2Anti-Feline DAW1 monoclonal antibodyFeline
GM-Tg-cang-SE0582-Ab-1/ GM-Tg-cang-SE0582-Ab-2Anti-Canine DAW1 monoclonal antibodyCanine
GM-Tg-bovg-SE0582-Ab-1/ GM-Tg-bovg-SE0582-Ab-2Anti-Bovine DAW1 monoclonal antibodyBovine
GM-Tg-equg-SE0582-Ab-1/ GM-Tg-equg-SE0582-Ab-2Anti-Equine DAW1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0582-Ab-1/ GM-Tg-hg-SE0582-Ab-2; GM-Tg-rg-SE0582-Ab-1/ GM-Tg-rg-SE0582-Ab-2;
GM-Tg-mg-SE0582-Ab-1/ GM-Tg-mg-SE0582-Ab-2; GM-Tg-cynog-SE0582-Ab-1/ GM-Tg-cynog-SE0582-Ab-2;
GM-Tg-felg-SE0582-Ab-1/ GM-Tg-felg-SE0582-Ab-2; GM-Tg-cang-SE0582-Ab-1/ GM-Tg-cang-SE0582-Ab-2;
GM-Tg-bovg-SE0582-Ab-1/ GM-Tg-bovg-SE0582-Ab-2; GM-Tg-equg-SE0582-Ab-1/ GM-Tg-equg-SE0582-Ab-2
Products NameAnti-DAW1 monoclonal antibody
Formatmab
Target NameDAW1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DAW1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0582-Ag-1Recombinant multi-species DAW1/ ODA16/ WDR69 protein


    Target information

    Target IDGM-SE0582
    Target NameDAW1
    Gene ID164781,71227,363267,713522,477397,101091963,530118,100062755
    Gene Symbol and Synonyms4930563E19Rik,4933429D11Rik,b2b1116Clo,b2b1584Clo,DAW1,DNAAF18,ODA16,WDR69
    Uniprot AccessionQ8N136,Q5BK30,Q0P593
    Uniprot Entry NameDAW1_HUMAN,DAW1_RAT,DAW1_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000123977
    Target ClassificationN/A

    The target: DAW1, gene name: DAW1, also named as ODA16, WDR69. Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; determination of left/right symmetry; and outer dynein arm assembly. Predicted to be located in cilium and extracellular region. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.