Anti-NUDT9/ NUDT10 functional antibody
Anti-NUDT9/ NUDT10 functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0596-Ab-1/ GM-Tg-hg-SE0596-Ab-2 | Anti-Human NUDT9 monoclonal antibody | Human |
GM-Tg-rg-SE0596-Ab-1/ GM-Tg-rg-SE0596-Ab-2 | Anti-Rat NUDT9 monoclonal antibody | Rat |
GM-Tg-mg-SE0596-Ab-1/ GM-Tg-mg-SE0596-Ab-2 | Anti-Mouse NUDT9 monoclonal antibody | Mouse |
GM-Tg-cynog-SE0596-Ab-1/ GM-Tg-cynog-SE0596-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NUDT9 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0596-Ab-1/ GM-Tg-felg-SE0596-Ab-2 | Anti-Feline NUDT9 monoclonal antibody | Feline |
GM-Tg-cang-SE0596-Ab-1/ GM-Tg-cang-SE0596-Ab-2 | Anti-Canine NUDT9 monoclonal antibody | Canine |
GM-Tg-bovg-SE0596-Ab-1/ GM-Tg-bovg-SE0596-Ab-2 | Anti-Bovine NUDT9 monoclonal antibody | Bovine |
GM-Tg-equg-SE0596-Ab-1/ GM-Tg-equg-SE0596-Ab-2 | Anti-Equine NUDT9 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE0596-Ab-1/ GM-Tg-hg-SE0596-Ab-2; GM-Tg-rg-SE0596-Ab-1/ GM-Tg-rg-SE0596-Ab-2; GM-Tg-mg-SE0596-Ab-1/ GM-Tg-mg-SE0596-Ab-2; GM-Tg-cynog-SE0596-Ab-1/ GM-Tg-cynog-SE0596-Ab-2; GM-Tg-felg-SE0596-Ab-1/ GM-Tg-felg-SE0596-Ab-2; GM-Tg-cang-SE0596-Ab-1/ GM-Tg-cang-SE0596-Ab-2; GM-Tg-bovg-SE0596-Ab-1/ GM-Tg-bovg-SE0596-Ab-2; GM-Tg-equg-SE0596-Ab-1/ GM-Tg-equg-SE0596-Ab-2 |
Products Name | Anti-NUDT9 monoclonal antibody |
Format | mab |
Target Name | NUDT9 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-NUDT9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE0596-Ag-1 | Recombinant multi-species NUDT9/ NUDT10 protein |
Target information
Target ID | GM-SE0596 |
Target Name | NUDT9 |
Gene ID | 53343,74167,305149,701344,478469,101099458,517589,100052874 |
Gene Symbol and Synonyms | 1190002C07Rik,ADPR-PPase,NUDT10,NUDT9 |
Uniprot Accession | Q9BW91,Q5XIG0 |
Uniprot Entry Name | NUDT9_HUMAN,NUDT9_RAT |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000170502 |
Target Classification | N/A |
The target: NUDT9, gene name: NUDT9, also named as NUDT10. The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.