Anti-SMOC1/ OAS functional antibody

Anti-SMOC1/ OAS functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to SMOC1/SMOC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0605-Ab-1/ GM-Tg-hg-SE0605-Ab-2Anti-Human SMOC1 monoclonal antibodyHuman
GM-Tg-rg-SE0605-Ab-1/ GM-Tg-rg-SE0605-Ab-2Anti-Rat SMOC1 monoclonal antibodyRat
GM-Tg-mg-SE0605-Ab-1/ GM-Tg-mg-SE0605-Ab-2Anti-Mouse SMOC1 monoclonal antibodyMouse
GM-Tg-cynog-SE0605-Ab-1/ GM-Tg-cynog-SE0605-Ab-2Anti-Cynomolgus/ Rhesus macaque SMOC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0605-Ab-1/ GM-Tg-felg-SE0605-Ab-2Anti-Feline SMOC1 monoclonal antibodyFeline
GM-Tg-cang-SE0605-Ab-1/ GM-Tg-cang-SE0605-Ab-2Anti-Canine SMOC1 monoclonal antibodyCanine
GM-Tg-bovg-SE0605-Ab-1/ GM-Tg-bovg-SE0605-Ab-2Anti-Bovine SMOC1 monoclonal antibodyBovine
GM-Tg-equg-SE0605-Ab-1/ GM-Tg-equg-SE0605-Ab-2Anti-Equine SMOC1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0605-Ab-1/ GM-Tg-hg-SE0605-Ab-2; GM-Tg-rg-SE0605-Ab-1/ GM-Tg-rg-SE0605-Ab-2;
GM-Tg-mg-SE0605-Ab-1/ GM-Tg-mg-SE0605-Ab-2; GM-Tg-cynog-SE0605-Ab-1/ GM-Tg-cynog-SE0605-Ab-2;
GM-Tg-felg-SE0605-Ab-1/ GM-Tg-felg-SE0605-Ab-2; GM-Tg-cang-SE0605-Ab-1/ GM-Tg-cang-SE0605-Ab-2;
GM-Tg-bovg-SE0605-Ab-1/ GM-Tg-bovg-SE0605-Ab-2; GM-Tg-equg-SE0605-Ab-1/ GM-Tg-equg-SE0605-Ab-2
Products NameAnti-SMOC1 monoclonal antibody
Formatmab
Target NameSMOC1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SMOC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0605-Ag-1Recombinant multi-species SMOC1/ OAS protein
    ORF Viral VectorvGMLP004132human SMOC1 Lentivirus particle
    ORF Viral VectorpGMLP004132human SMOC1 Lentivirus plasmid


    Target information

    Target IDGM-SE0605
    Target NameSMOC1
    Gene ID64093,64075,314280,712994,480373,101080800,508379,100629852
    Gene Symbol and Synonyms2600002F22Rik,OAS,SMOC1,SRG
    Uniprot AccessionQ9H4F8
    Uniprot Entry NameSMOC1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198732
    Target ClassificationN/A

    The target: SMOC1, gene name: SMOC1, also named as OAS. This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.