- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SUMF2/ pFGE functional antibody
Anti-SUMF2/ pFGE functional antibody for cell culture, ELISA & in-vivo assay
Go to SUMF2/SUMF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0608-Ab-1/ GM-Tg-hg-SE0608-Ab-2 | Anti-Human SUMF2 monoclonal antibody | Human |
| GM-Tg-rg-SE0608-Ab-1/ GM-Tg-rg-SE0608-Ab-2 | Anti-Rat SUMF2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0608-Ab-1/ GM-Tg-mg-SE0608-Ab-2 | Anti-Mouse SUMF2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0608-Ab-1/ GM-Tg-cynog-SE0608-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SUMF2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0608-Ab-1/ GM-Tg-felg-SE0608-Ab-2 | Anti-Feline SUMF2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0608-Ab-1/ GM-Tg-cang-SE0608-Ab-2 | Anti-Canine SUMF2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0608-Ab-1/ GM-Tg-bovg-SE0608-Ab-2 | Anti-Bovine SUMF2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0608-Ab-1/ GM-Tg-equg-SE0608-Ab-2 | Anti-Equine SUMF2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0608-Ab-1/ GM-Tg-hg-SE0608-Ab-2; GM-Tg-rg-SE0608-Ab-1/ GM-Tg-rg-SE0608-Ab-2; GM-Tg-mg-SE0608-Ab-1/ GM-Tg-mg-SE0608-Ab-2; GM-Tg-cynog-SE0608-Ab-1/ GM-Tg-cynog-SE0608-Ab-2; GM-Tg-felg-SE0608-Ab-1/ GM-Tg-felg-SE0608-Ab-2; GM-Tg-cang-SE0608-Ab-1/ GM-Tg-cang-SE0608-Ab-2; GM-Tg-bovg-SE0608-Ab-1/ GM-Tg-bovg-SE0608-Ab-2; GM-Tg-equg-SE0608-Ab-1/ GM-Tg-equg-SE0608-Ab-2 |
| Products Name | Anti-SUMF2 monoclonal antibody |
| Format | mab |
| Target Name | SUMF2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SUMF2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0608-Ag-1 | Recombinant multi-species SUMF2/ pFGE protein |
| ORF Viral Vector | pGMLPm000964 | mouse Sumf2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000964 | mouse Sumf2 Lentivirus particle |
Target information
| Target ID | GM-SE0608 |
| Target Name | SUMF2 |
| Gene ID | 25870,67902,360800,715253,479701,101085769,509497,100061372 |
| Gene Symbol and Synonyms | 2610040F05Rik,pFGE,SUMF2 |
| Uniprot Accession | Q8NBJ7,Q58CP2 |
| Uniprot Entry Name | SUMF2_HUMAN,SUMF2_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000129103 |
| Target Classification | N/A |
The target: SUMF2, gene name: SUMF2, also named as pFGE. The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
