Anti-IFNK/ IFNT1/ INFE1 functional antibody

Anti-IFNK/ IFNT1/ INFE1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IFNK/IFNK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0619-Ab-1/ GM-Tg-hg-SE0619-Ab-2Anti-Human IFNK monoclonal antibodyHuman
GM-Tg-rg-SE0619-Ab-1/ GM-Tg-rg-SE0619-Ab-2Anti-Rat IFNK monoclonal antibodyRat
GM-Tg-mg-SE0619-Ab-1/ GM-Tg-mg-SE0619-Ab-2Anti-Mouse IFNK monoclonal antibodyMouse
GM-Tg-cynog-SE0619-Ab-1/ GM-Tg-cynog-SE0619-Ab-2Anti-Cynomolgus/ Rhesus macaque IFNK monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0619-Ab-1/ GM-Tg-felg-SE0619-Ab-2Anti-Feline IFNK monoclonal antibodyFeline
GM-Tg-cang-SE0619-Ab-1/ GM-Tg-cang-SE0619-Ab-2Anti-Canine IFNK monoclonal antibodyCanine
GM-Tg-bovg-SE0619-Ab-1/ GM-Tg-bovg-SE0619-Ab-2Anti-Bovine IFNK monoclonal antibodyBovine
GM-Tg-equg-SE0619-Ab-1/ GM-Tg-equg-SE0619-Ab-2Anti-Equine IFNK monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0619-Ab-1/ GM-Tg-hg-SE0619-Ab-2; GM-Tg-rg-SE0619-Ab-1/ GM-Tg-rg-SE0619-Ab-2;
GM-Tg-mg-SE0619-Ab-1/ GM-Tg-mg-SE0619-Ab-2; GM-Tg-cynog-SE0619-Ab-1/ GM-Tg-cynog-SE0619-Ab-2;
GM-Tg-felg-SE0619-Ab-1/ GM-Tg-felg-SE0619-Ab-2; GM-Tg-cang-SE0619-Ab-1/ GM-Tg-cang-SE0619-Ab-2;
GM-Tg-bovg-SE0619-Ab-1/ GM-Tg-bovg-SE0619-Ab-2; GM-Tg-equg-SE0619-Ab-1/ GM-Tg-equg-SE0619-Ab-2
Products NameAnti-IFNK monoclonal antibody
Formatmab
Target NameIFNK
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IFNK benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0619-Ag-1Recombinant multi-species IFNK/ IFNT1/ INFE1 protein
    CytokineGM-Tg-g-SE0619-Ag-1interferon, kappa (IFNK) protein


    Target information

    Target IDGM-SE0619
    Target NameIFNK
    Gene ID56832,387510,313152,707234,100855436,101092553,100138192,100067055
    Gene Symbol and SynonymsIf1fa,IFNK,IFNT1,INFE1
    Uniprot AccessionQ9P0W0
    Uniprot Entry NameIFNK_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000147896
    Target ClassificationN/A

    The target: IFNK, gene name: IFNK, also named as IFNT1, INFE1. This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.