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Anti-LTBP2/ C14orf141/ GLC3D functional antibody
Anti-LTBP2/ C14orf141/ GLC3D functional antibody for cell culture, ELISA & in-vivo assay
Go to LTBP2/LTBP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0621-Ab-1/ GM-Tg-hg-SE0621-Ab-2 | Anti-Human LTBP2 monoclonal antibody | Human |
| GM-Tg-rg-SE0621-Ab-1/ GM-Tg-rg-SE0621-Ab-2 | Anti-Rat LTBP2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0621-Ab-1/ GM-Tg-mg-SE0621-Ab-2 | Anti-Mouse LTBP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0621-Ab-1/ GM-Tg-cynog-SE0621-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LTBP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0621-Ab-1/ GM-Tg-felg-SE0621-Ab-2 | Anti-Feline LTBP2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0621-Ab-1/ GM-Tg-cang-SE0621-Ab-2 | Anti-Canine LTBP2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0621-Ab-1/ GM-Tg-bovg-SE0621-Ab-2 | Anti-Bovine LTBP2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0621-Ab-1/ GM-Tg-equg-SE0621-Ab-2 | Anti-Equine LTBP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0621-Ab-1/ GM-Tg-hg-SE0621-Ab-2; GM-Tg-rg-SE0621-Ab-1/ GM-Tg-rg-SE0621-Ab-2; GM-Tg-mg-SE0621-Ab-1/ GM-Tg-mg-SE0621-Ab-2; GM-Tg-cynog-SE0621-Ab-1/ GM-Tg-cynog-SE0621-Ab-2; GM-Tg-felg-SE0621-Ab-1/ GM-Tg-felg-SE0621-Ab-2; GM-Tg-cang-SE0621-Ab-1/ GM-Tg-cang-SE0621-Ab-2; GM-Tg-bovg-SE0621-Ab-1/ GM-Tg-bovg-SE0621-Ab-2; GM-Tg-equg-SE0621-Ab-1/ GM-Tg-equg-SE0621-Ab-2 |
| Products Name | Anti-LTBP2 monoclonal antibody |
| Format | mab |
| Target Name | LTBP2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-LTBP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0621-Ag-1 | Recombinant multi-species LTBP2/ C14orf141/ GLC3D protein |
Target information
| Target ID | GM-SE0621 |
| Target Name | LTBP2 |
| Gene ID | 4053,16997,59106,699435,490784,101083010,281905,100056889 |
| Gene Symbol and Synonyms | C14orf141,GLC3D,LTBP2,LTBP3,MSPKA,MSTP031,WMS3 |
| Uniprot Accession | Q14767,O35806,Q28019 |
| Uniprot Entry Name | LTBP2_HUMAN,LTBP2_RAT,LTBP2_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Ovary Cancer, Mucocutaneous lymph node syndrome [Kawasaki] |
| Gene Ensembl | ENSG00000119681 |
| Target Classification | N/A |
The target: LTBP2, gene name: LTBP2, also named as C14orf141, GLC3D, LTBP3, MSPKA, MSTP031, WMS3. The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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