- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-OX26/ QRFP/ 26RFa functional antibody
Anti-OX26/ QRFP/ 26RFa functional antibody for cell culture, ELISA & in-vivo assay
Go to QRFP/QRFP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0623-Ab-1/ GM-Tg-hg-SE0623-Ab-2 | Anti-Human QRFP monoclonal antibody | Human |
| GM-Tg-rg-SE0623-Ab-1/ GM-Tg-rg-SE0623-Ab-2 | Anti-Rat QRFP monoclonal antibody | Rat |
| GM-Tg-mg-SE0623-Ab-1/ GM-Tg-mg-SE0623-Ab-2 | Anti-Mouse QRFP monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0623-Ab-1/ GM-Tg-cynog-SE0623-Ab-2 | Anti-Cynomolgus/ Rhesus macaque QRFP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0623-Ab-1/ GM-Tg-felg-SE0623-Ab-2 | Anti-Feline QRFP monoclonal antibody | Feline |
| GM-Tg-cang-SE0623-Ab-1/ GM-Tg-cang-SE0623-Ab-2 | Anti-Canine QRFP monoclonal antibody | Canine |
| GM-Tg-bovg-SE0623-Ab-1/ GM-Tg-bovg-SE0623-Ab-2 | Anti-Bovine QRFP monoclonal antibody | Bovine |
| GM-Tg-equg-SE0623-Ab-1/ GM-Tg-equg-SE0623-Ab-2 | Anti-Equine QRFP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0623-Ab-1/ GM-Tg-hg-SE0623-Ab-2; GM-Tg-rg-SE0623-Ab-1/ GM-Tg-rg-SE0623-Ab-2; GM-Tg-mg-SE0623-Ab-1/ GM-Tg-mg-SE0623-Ab-2; GM-Tg-cynog-SE0623-Ab-1/ GM-Tg-cynog-SE0623-Ab-2; GM-Tg-felg-SE0623-Ab-1/ GM-Tg-felg-SE0623-Ab-2; GM-Tg-cang-SE0623-Ab-1/ GM-Tg-cang-SE0623-Ab-2; GM-Tg-bovg-SE0623-Ab-1/ GM-Tg-bovg-SE0623-Ab-2; GM-Tg-equg-SE0623-Ab-1/ GM-Tg-equg-SE0623-Ab-2 |
| Products Name | Anti-QRFP monoclonal antibody |
| Format | mab |
| Target Name | QRFP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-QRFP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0623-Ag-1 | Recombinant multi-species OX26/ QRFP/ 26RFa protein |
Target information
| Target ID | GM-SE0623 |
| Target Name | QRFP |
| Gene ID | 347148,227717,379044,715836,608592,101098017,379045,100069698 |
| Gene Symbol and Synonyms | 26RFa,NEWGENE_735020,P518,QRFP |
| Uniprot Accession | P83859,P83860,P83862 |
| Uniprot Entry Name | OX26_HUMAN,OX26_RAT,OX26_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000188710 |
| Target Classification | N/A |
The target: QRFP, gene name: QRFP, also named as 26RFa, P518. This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
