Anti-A1BG/ A1B/ ABG functional antibody
Anti-A1BG/ A1B/ ABG functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0630-Ab-1/ GM-Tg-hg-SE0630-Ab-2 | Anti-Human A1BG monoclonal antibody | Human |
GM-Tg-rg-SE0630-Ab-1/ GM-Tg-rg-SE0630-Ab-2 | Anti-Rat A1BG monoclonal antibody | Rat |
GM-Tg-mg-SE0630-Ab-1/ GM-Tg-mg-SE0630-Ab-2 | Anti-Mouse A1BG monoclonal antibody | Mouse |
GM-Tg-cynog-SE0630-Ab-1/ GM-Tg-cynog-SE0630-Ab-2 | Anti-Cynomolgus/ Rhesus macaque A1BG monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0630-Ab-1/ GM-Tg-felg-SE0630-Ab-2 | Anti-Feline A1BG monoclonal antibody | Feline |
GM-Tg-cang-SE0630-Ab-1/ GM-Tg-cang-SE0630-Ab-2 | Anti-Canine A1BG monoclonal antibody | Canine |
GM-Tg-bovg-SE0630-Ab-1/ GM-Tg-bovg-SE0630-Ab-2 | Anti-Bovine A1BG monoclonal antibody | Bovine |
GM-Tg-equg-SE0630-Ab-1/ GM-Tg-equg-SE0630-Ab-2 | Anti-Equine A1BG monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE0630-Ab-1/ GM-Tg-hg-SE0630-Ab-2; GM-Tg-rg-SE0630-Ab-1/ GM-Tg-rg-SE0630-Ab-2; GM-Tg-mg-SE0630-Ab-1/ GM-Tg-mg-SE0630-Ab-2; GM-Tg-cynog-SE0630-Ab-1/ GM-Tg-cynog-SE0630-Ab-2; GM-Tg-felg-SE0630-Ab-1/ GM-Tg-felg-SE0630-Ab-2; GM-Tg-cang-SE0630-Ab-1/ GM-Tg-cang-SE0630-Ab-2; GM-Tg-bovg-SE0630-Ab-1/ GM-Tg-bovg-SE0630-Ab-2; GM-Tg-equg-SE0630-Ab-1/ GM-Tg-equg-SE0630-Ab-2 |
Products Name | Anti-A1BG monoclonal antibody |
Format | mab |
Target Name | A1BG |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-A1BG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE0630-Ag-1 | Recombinant multi-species A1BG/ A1B/ ABG protein |
Target information
Target ID | GM-SE0630 |
Target Name | A1BG |
Gene ID | 1,117586,712737,484230,101089972,518955,100064369 |
Gene Symbol and Synonyms | A1B,A1BG,ABG,C44,GAB,HYST2477 |
Uniprot Accession | P04217,Q2KJF1,P39091 |
Uniprot Entry Name | A1BG_HUMAN,A1BG_BOVIN,A1BG_HORSE |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | Lung cancer, Type 1 diabetes mellitus, Diabetic Nephropathy, IgA glomerulonephritis, Nephrotic syndrome, Malignant neoplasm of bladder |
Gene Ensembl | ENSG00000121410 |
Target Classification | N/A |
The target: A1BG, gene name: A1BG, also named as A1B, ABG, GAB, HYST2477. The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.