Anti-AMY1A/ AMY1 functional antibody

Anti-AMY1A/ AMY1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to AMY1A/AMY1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0662-Ab-1/ GM-Tg-hg-SE0662-Ab-2Anti-Human AMY1A monoclonal antibodyHuman
GM-Tg-rg-SE0662-Ab-1/ GM-Tg-rg-SE0662-Ab-2Anti-Rat AMY1A monoclonal antibodyRat
GM-Tg-mg-SE0662-Ab-1/ GM-Tg-mg-SE0662-Ab-2Anti-Mouse AMY1A monoclonal antibodyMouse
GM-Tg-cynog-SE0662-Ab-1/ GM-Tg-cynog-SE0662-Ab-2Anti-Cynomolgus/ Rhesus macaque AMY1A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0662-Ab-1/ GM-Tg-felg-SE0662-Ab-2Anti-Feline AMY1A monoclonal antibodyFeline
GM-Tg-cang-SE0662-Ab-1/ GM-Tg-cang-SE0662-Ab-2Anti-Canine AMY1A monoclonal antibodyCanine
GM-Tg-bovg-SE0662-Ab-1/ GM-Tg-bovg-SE0662-Ab-2Anti-Bovine AMY1A monoclonal antibodyBovine
GM-Tg-equg-SE0662-Ab-1/ GM-Tg-equg-SE0662-Ab-2Anti-Equine AMY1A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0662-Ab-1/ GM-Tg-hg-SE0662-Ab-2; GM-Tg-rg-SE0662-Ab-1/ GM-Tg-rg-SE0662-Ab-2;
GM-Tg-mg-SE0662-Ab-1/ GM-Tg-mg-SE0662-Ab-2; GM-Tg-cynog-SE0662-Ab-1/ GM-Tg-cynog-SE0662-Ab-2;
GM-Tg-felg-SE0662-Ab-1/ GM-Tg-felg-SE0662-Ab-2; GM-Tg-cang-SE0662-Ab-1/ GM-Tg-cang-SE0662-Ab-2;
GM-Tg-bovg-SE0662-Ab-1/ GM-Tg-bovg-SE0662-Ab-2; GM-Tg-equg-SE0662-Ab-1/ GM-Tg-equg-SE0662-Ab-2
Products NameAnti-AMY1A monoclonal antibody
Formatmab
Target NameAMY1A
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-AMY1A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0662-Ag-1Recombinant multi-species AMY1A/ AMY1 protein


    Target information

    Target IDGM-SE0662
    Target NameAMY1A
    Gene ID276
    Gene Symbol and SynonymsAMY1,AMY1A
    Uniprot AccessionP0DUB6
    Uniprot Entry NameAMY1A_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000237763
    Target ClassificationN/A

    The target: AMY1A, gene name: AMY1A, also named as AMY1. Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.