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Anti-ANGP4/ ANGPT4/ ANG3 functional antibody
Anti-ANGP4/ ANGPT4/ ANG3 functional antibody for cell culture, ELISA & in-vivo assay
Go to ANGPT4/ANGPT4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0666-Ab-1/ GM-Tg-hg-SE0666-Ab-2 | Anti-Human ANGPT4 monoclonal antibody | Human |
| GM-Tg-rg-SE0666-Ab-1/ GM-Tg-rg-SE0666-Ab-2 | Anti-Rat ANGPT4 monoclonal antibody | Rat |
| GM-Tg-mg-SE0666-Ab-1/ GM-Tg-mg-SE0666-Ab-2 | Anti-Mouse ANGPT4 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0666-Ab-1/ GM-Tg-cynog-SE0666-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ANGPT4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0666-Ab-1/ GM-Tg-felg-SE0666-Ab-2 | Anti-Feline ANGPT4 monoclonal antibody | Feline |
| GM-Tg-cang-SE0666-Ab-1/ GM-Tg-cang-SE0666-Ab-2 | Anti-Canine ANGPT4 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0666-Ab-1/ GM-Tg-bovg-SE0666-Ab-2 | Anti-Bovine ANGPT4 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0666-Ab-1/ GM-Tg-equg-SE0666-Ab-2 | Anti-Equine ANGPT4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0666-Ab-1/ GM-Tg-hg-SE0666-Ab-2; GM-Tg-rg-SE0666-Ab-1/ GM-Tg-rg-SE0666-Ab-2; GM-Tg-mg-SE0666-Ab-1/ GM-Tg-mg-SE0666-Ab-2; GM-Tg-cynog-SE0666-Ab-1/ GM-Tg-cynog-SE0666-Ab-2; GM-Tg-felg-SE0666-Ab-1/ GM-Tg-felg-SE0666-Ab-2; GM-Tg-cang-SE0666-Ab-1/ GM-Tg-cang-SE0666-Ab-2; GM-Tg-bovg-SE0666-Ab-1/ GM-Tg-bovg-SE0666-Ab-2; GM-Tg-equg-SE0666-Ab-1/ GM-Tg-equg-SE0666-Ab-2 |
| Products Name | Anti-ANGPT4 monoclonal antibody |
| Format | mab |
| Target Name | ANGPT4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ANGPT4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0666-Ag-1 | Recombinant multi-species ANGP4/ ANGPT4/ ANG3 protein |
Target information
| Target ID | GM-SE0666 |
| Target Name | ANGPT4 |
| Gene ID | 51378,11602,296269,715213,609626,101091274,617915,100067818 |
| Gene Symbol and Synonyms | Agpt4,ANG-3,ANG-4,ANG3,ANG4,ANGPT4,ANGPTL4 |
| Uniprot Accession | Q9Y264,Q24K15 |
| Uniprot Entry Name | ANGP4_HUMAN,ANGP4_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000101280 |
| Target Classification | N/A |
The target: ANGPT4, gene name: ANGPT4, also named as ANG3, ANG4. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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