- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-APOA5/ APOAV/ RAP3 functional antibody
Anti-APOA5/ APOAV/ RAP3 functional antibody for cell culture, ELISA & in-vivo assay
Go to APOA5/APOA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0671-Ab-1/ GM-Tg-hg-SE0671-Ab-2 | Anti-Human APOA5 monoclonal antibody | Human |
| GM-Tg-rg-SE0671-Ab-1/ GM-Tg-rg-SE0671-Ab-2 | Anti-Rat APOA5 monoclonal antibody | Rat |
| GM-Tg-mg-SE0671-Ab-1/ GM-Tg-mg-SE0671-Ab-2 | Anti-Mouse APOA5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0671-Ab-1/ GM-Tg-cynog-SE0671-Ab-2 | Anti-Cynomolgus/ Rhesus macaque APOA5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0671-Ab-1/ GM-Tg-felg-SE0671-Ab-2 | Anti-Feline APOA5 monoclonal antibody | Feline |
| GM-Tg-cang-SE0671-Ab-1/ GM-Tg-cang-SE0671-Ab-2 | Anti-Canine APOA5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0671-Ab-1/ GM-Tg-bovg-SE0671-Ab-2 | Anti-Bovine APOA5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0671-Ab-1/ GM-Tg-equg-SE0671-Ab-2 | Anti-Equine APOA5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0671-Ab-1/ GM-Tg-hg-SE0671-Ab-2; GM-Tg-rg-SE0671-Ab-1/ GM-Tg-rg-SE0671-Ab-2; GM-Tg-mg-SE0671-Ab-1/ GM-Tg-mg-SE0671-Ab-2; GM-Tg-cynog-SE0671-Ab-1/ GM-Tg-cynog-SE0671-Ab-2; GM-Tg-felg-SE0671-Ab-1/ GM-Tg-felg-SE0671-Ab-2; GM-Tg-cang-SE0671-Ab-1/ GM-Tg-cang-SE0671-Ab-2; GM-Tg-bovg-SE0671-Ab-1/ GM-Tg-bovg-SE0671-Ab-2; GM-Tg-equg-SE0671-Ab-1/ GM-Tg-equg-SE0671-Ab-2 |
| Products Name | Anti-APOA5 monoclonal antibody |
| Format | mab |
| Target Name | APOA5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-APOA5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0671-Ag-1 | Recombinant multi-species APOA5/ APOAV/ RAP3 protein |
| ORF Viral Vector | pGMLPm001817 | mouse Apoa5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001817 | mouse Apoa5 Lentivirus particle |
Target information
| Target ID | GM-SE0671 |
| Target Name | APOA5 |
| Gene ID | 116519,66113,140638,696484,489393,101085400,538914,100071101 |
| Gene Symbol and Synonyms | 1300007O05Rik,apo-AV,apoA-V,APOA5,APOAV,RAP3 |
| Uniprot Accession | Q6Q788,Q9QUH3 |
| Uniprot Entry Name | APOA5_HUMAN,APOA5_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000110243 |
| Target Classification | N/A |
The target: APOA5, gene name: APOA5, also named as APOAV, RAP3. The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
