Anti-APOF/ Apo-F/ LTIP functional antibody

Anti-APOF/ Apo-F/ LTIP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to APOF/APOF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0675-Ab-1/ GM-Tg-hg-SE0675-Ab-2Anti-Human APOF monoclonal antibodyHuman
GM-Tg-rg-SE0675-Ab-1/ GM-Tg-rg-SE0675-Ab-2Anti-Rat APOF monoclonal antibodyRat
GM-Tg-mg-SE0675-Ab-1/ GM-Tg-mg-SE0675-Ab-2Anti-Mouse APOF monoclonal antibodyMouse
GM-Tg-cynog-SE0675-Ab-1/ GM-Tg-cynog-SE0675-Ab-2Anti-Cynomolgus/ Rhesus macaque APOF monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0675-Ab-1/ GM-Tg-felg-SE0675-Ab-2Anti-Feline APOF monoclonal antibodyFeline
GM-Tg-cang-SE0675-Ab-1/ GM-Tg-cang-SE0675-Ab-2Anti-Canine APOF monoclonal antibodyCanine
GM-Tg-bovg-SE0675-Ab-1/ GM-Tg-bovg-SE0675-Ab-2Anti-Bovine APOF monoclonal antibodyBovine
GM-Tg-equg-SE0675-Ab-1/ GM-Tg-equg-SE0675-Ab-2Anti-Equine APOF monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0675-Ab-1/ GM-Tg-hg-SE0675-Ab-2; GM-Tg-rg-SE0675-Ab-1/ GM-Tg-rg-SE0675-Ab-2;
GM-Tg-mg-SE0675-Ab-1/ GM-Tg-mg-SE0675-Ab-2; GM-Tg-cynog-SE0675-Ab-1/ GM-Tg-cynog-SE0675-Ab-2;
GM-Tg-felg-SE0675-Ab-1/ GM-Tg-felg-SE0675-Ab-2; GM-Tg-cang-SE0675-Ab-1/ GM-Tg-cang-SE0675-Ab-2;
GM-Tg-bovg-SE0675-Ab-1/ GM-Tg-bovg-SE0675-Ab-2; GM-Tg-equg-SE0675-Ab-1/ GM-Tg-equg-SE0675-Ab-2
Products NameAnti-APOF monoclonal antibody
Formatmab
Target NameAPOF
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-APOF benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0675-Ag-1Recombinant multi-species APOF/ Apo-F/ LTIP protein
    ORF Viral VectorvGMLP0025660 APOF Lentivirus particle
    ORF Viral VectorpGMLP002566human APOF Lentivirus plasmid
    ORF Viral VectorpGMLPm002834mouse Apof Lentivirus plasmid
    ORF Viral VectorvGMLPm002834mouse Apof Lentivirus particle


    Target information

    Target IDGM-SE0675
    Target NameAPOF
    Gene ID319,103161,712761,474405,101086159,100059518
    Gene Symbol and SynonymsApo-F,APOF,LTIP
    Uniprot AccessionQ13790
    Uniprot Entry NameAPOF_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000175336
    Target ClassificationN/A

    The target: APOF, gene name: APOF, also named as Apo-F, LTIP. The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.