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Anti-ARSI/ ASI/ SPG66 functional antibody
Anti-ARSI/ ASI/ SPG66 functional antibody for cell culture, ELISA & in-vivo assay
Go to ARSI/ARSI products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0677-Ab-1/ GM-Tg-hg-SE0677-Ab-2 | Anti-Human ARSI monoclonal antibody | Human |
| GM-Tg-rg-SE0677-Ab-1/ GM-Tg-rg-SE0677-Ab-2 | Anti-Rat ARSI monoclonal antibody | Rat |
| GM-Tg-mg-SE0677-Ab-1/ GM-Tg-mg-SE0677-Ab-2 | Anti-Mouse ARSI monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0677-Ab-1/ GM-Tg-cynog-SE0677-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ARSI monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0677-Ab-1/ GM-Tg-felg-SE0677-Ab-2 | Anti-Feline ARSI monoclonal antibody | Feline |
| GM-Tg-cang-SE0677-Ab-1/ GM-Tg-cang-SE0677-Ab-2 | Anti-Canine ARSI monoclonal antibody | Canine |
| GM-Tg-bovg-SE0677-Ab-1/ GM-Tg-bovg-SE0677-Ab-2 | Anti-Bovine ARSI monoclonal antibody | Bovine |
| GM-Tg-equg-SE0677-Ab-1/ GM-Tg-equg-SE0677-Ab-2 | Anti-Equine ARSI monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0677-Ab-1/ GM-Tg-hg-SE0677-Ab-2; GM-Tg-rg-SE0677-Ab-1/ GM-Tg-rg-SE0677-Ab-2; GM-Tg-mg-SE0677-Ab-1/ GM-Tg-mg-SE0677-Ab-2; GM-Tg-cynog-SE0677-Ab-1/ GM-Tg-cynog-SE0677-Ab-2; GM-Tg-felg-SE0677-Ab-1/ GM-Tg-felg-SE0677-Ab-2; GM-Tg-cang-SE0677-Ab-1/ GM-Tg-cang-SE0677-Ab-2; GM-Tg-bovg-SE0677-Ab-1/ GM-Tg-bovg-SE0677-Ab-2; GM-Tg-equg-SE0677-Ab-1/ GM-Tg-equg-SE0677-Ab-2 |
| Products Name | Anti-ARSI monoclonal antibody |
| Format | mab |
| Target Name | ARSI |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ARSI benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0677-Ag-1 | Recombinant multi-species ARSI/ ASI/ SPG66 protein |
Target information
| Target ID | GM-SE0677 |
| Target Name | ARSI |
| Gene ID | 340075,545260,307404,712077,489186,101086206,540390,100071647 |
| Gene Symbol and Synonyms | ARSI,ASI,RGD1310242,SPG66 |
| Uniprot Accession | Q5FYB1,Q32KJ8,Q32KH7 |
| Uniprot Entry Name | ARSI_HUMAN,ARSI_RAT,ARSI_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000183876 |
| Target Classification | N/A |
The target: ARSI, gene name: ARSI, also named as ASI, SPG66. This gene encodes a protein that belongs to a large family of sulfatases that hydrolyze sulfate esters and sulfamates. Members of this family play a role in several cellular processes, including hormone synthesis, cell signaling in development and degradation of macromolecules. The protein encoded by this gene is thought to be secreted, and to function in extracellular space. [provided by RefSeq, Jul 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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