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Anti-BPIA1/ BPIFA1/ LUNX functional antibody
Anti-BPIA1/ BPIFA1/ LUNX functional antibody for cell culture, ELISA & in-vivo assay
Go to BPIFA1/BPIFA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0690-Ab-1/ GM-Tg-hg-SE0690-Ab-2 | Anti-Human BPIFA1 monoclonal antibody | Human |
| GM-Tg-rg-SE0690-Ab-1/ GM-Tg-rg-SE0690-Ab-2 | Anti-Rat BPIFA1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0690-Ab-1/ GM-Tg-mg-SE0690-Ab-2 | Anti-Mouse BPIFA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0690-Ab-1/ GM-Tg-cynog-SE0690-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BPIFA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0690-Ab-1/ GM-Tg-felg-SE0690-Ab-2 | Anti-Feline BPIFA1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0690-Ab-1/ GM-Tg-cang-SE0690-Ab-2 | Anti-Canine BPIFA1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0690-Ab-1/ GM-Tg-bovg-SE0690-Ab-2 | Anti-Bovine BPIFA1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0690-Ab-1/ GM-Tg-equg-SE0690-Ab-2 | Anti-Equine BPIFA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0690-Ab-1/ GM-Tg-hg-SE0690-Ab-2; GM-Tg-rg-SE0690-Ab-1/ GM-Tg-rg-SE0690-Ab-2; GM-Tg-mg-SE0690-Ab-1/ GM-Tg-mg-SE0690-Ab-2; GM-Tg-cynog-SE0690-Ab-1/ GM-Tg-cynog-SE0690-Ab-2; GM-Tg-felg-SE0690-Ab-1/ GM-Tg-felg-SE0690-Ab-2; GM-Tg-cang-SE0690-Ab-1/ GM-Tg-cang-SE0690-Ab-2; GM-Tg-bovg-SE0690-Ab-1/ GM-Tg-bovg-SE0690-Ab-2; GM-Tg-equg-SE0690-Ab-1/ GM-Tg-equg-SE0690-Ab-2 |
| Products Name | Anti-BPIFA1 monoclonal antibody |
| Format | mab |
| Target Name | BPIFA1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-BPIFA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0690-Ag-1 | Recombinant multi-species BPIA1/ BPIFA1/ LUNX protein |
| ORF Viral Vector | pGMLPm003497 | mouse Bpifa1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003497 | mouse Bpifa1 Lentivirus particle |
Target information
| Target ID | GM-SE0690 |
| Target Name | BPIFA1 |
| Gene ID | 51297,18843,246238,714509,609982,101091273,281989,100068890 |
| Gene Symbol and Synonyms | bA49G10.5,BPIFA1,LUNX,NASG,PLUNC,SPLUNC1,SPURT |
| Uniprot Accession | Q9NP55,Q8K4I4,Q8SPU5 |
| Uniprot Entry Name | BPIA1_HUMAN,BPIA1_RAT,BPIA1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000198183 |
| Target Classification | N/A |
The target: BPIFA1, gene name: BPIFA1, also named as LUNX, NASG, PLUNC, SPLUNC1, SPURT, bA49G10.5. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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