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Anti-BPIA2/ BPIFA2/ C20orf70 functional antibody
Anti-BPIA2/ BPIFA2/ C20orf70 functional antibody for cell culture, ELISA & in-vivo assay
Go to BPIFA2/BPIFA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0691-Ab-1/ GM-Tg-hg-SE0691-Ab-2 | Anti-Human BPIFA2 monoclonal antibody | Human |
| GM-Tg-rg-SE0691-Ab-1/ GM-Tg-rg-SE0691-Ab-2 | Anti-Rat BPIFA2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0691-Ab-1/ GM-Tg-mg-SE0691-Ab-2 | Anti-Mouse BPIFA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0691-Ab-1/ GM-Tg-cynog-SE0691-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BPIFA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0691-Ab-1/ GM-Tg-felg-SE0691-Ab-2 | Anti-Feline BPIFA2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0691-Ab-1/ GM-Tg-cang-SE0691-Ab-2 | Anti-Canine BPIFA2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0691-Ab-1/ GM-Tg-bovg-SE0691-Ab-2 | Anti-Bovine BPIFA2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0691-Ab-1/ GM-Tg-equg-SE0691-Ab-2 | Anti-Equine BPIFA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0691-Ab-1/ GM-Tg-hg-SE0691-Ab-2; GM-Tg-rg-SE0691-Ab-1/ GM-Tg-rg-SE0691-Ab-2; GM-Tg-mg-SE0691-Ab-1/ GM-Tg-mg-SE0691-Ab-2; GM-Tg-cynog-SE0691-Ab-1/ GM-Tg-cynog-SE0691-Ab-2; GM-Tg-felg-SE0691-Ab-1/ GM-Tg-felg-SE0691-Ab-2; GM-Tg-cang-SE0691-Ab-1/ GM-Tg-cang-SE0691-Ab-2; GM-Tg-bovg-SE0691-Ab-1/ GM-Tg-bovg-SE0691-Ab-2; GM-Tg-equg-SE0691-Ab-1/ GM-Tg-equg-SE0691-Ab-2 |
| Products Name | Anti-BPIFA2 monoclonal antibody |
| Format | mab |
| Target Name | BPIFA2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-BPIFA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0691-Ag-1 | Recombinant multi-species BPIA2/ BPIFA2/ C20orf70 protein |
Target information
| Target ID | GM-SE0691 |
| Target Name | BPIFA2 |
| Gene ID | 140683,19194,50585,710376,608599,101099708 |
| Gene Symbol and Synonyms | bA49G10.1,BPIFA2,Bpifa2e,C20orf70,PSP,SPLUNC2 |
| Uniprot Accession | Q96DR5,Q63471 |
| Uniprot Entry Name | BPIA2_HUMAN,BPIA2_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000131050 |
| Target Classification | N/A |
The target: BPIFA2, gene name: BPIFA2, also named as C20orf70, PSP, SPLUNC2, bA49G10.1. This gene encodes a member of the palate, lung and nasal epithelium clone (Plunc) family of proteins. Members of this family have been proposed to play a role in the local antibacterial response in nose, mouth and upper respiratory pathways. The encoded soluble salivary protein binds bacterial lipopolysaccharide (LPS) and inhibits bacterial growth. This gene is present in a gene cluster on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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