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Anti-C1QA functional antibody
Anti-C1QA functional antibody for cell culture, ELISA & in-vivo assay
Go to C1QA/C1QA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0706-Ab-1/ GM-Tg-hg-SE0706-Ab-2 | Anti-Human C1QA monoclonal antibody | Human |
| GM-Tg-rg-SE0706-Ab-1/ GM-Tg-rg-SE0706-Ab-2 | Anti-Rat C1QA monoclonal antibody | Rat |
| GM-Tg-mg-SE0706-Ab-1/ GM-Tg-mg-SE0706-Ab-2 | Anti-Mouse C1QA monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0706-Ab-1/ GM-Tg-cynog-SE0706-Ab-2 | Anti-Cynomolgus/ Rhesus macaque C1QA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0706-Ab-1/ GM-Tg-felg-SE0706-Ab-2 | Anti-Feline C1QA monoclonal antibody | Feline |
| GM-Tg-cang-SE0706-Ab-1/ GM-Tg-cang-SE0706-Ab-2 | Anti-Canine C1QA monoclonal antibody | Canine |
| GM-Tg-bovg-SE0706-Ab-1/ GM-Tg-bovg-SE0706-Ab-2 | Anti-Bovine C1QA monoclonal antibody | Bovine |
| GM-Tg-equg-SE0706-Ab-1/ GM-Tg-equg-SE0706-Ab-2 | Anti-Equine C1QA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0706-Ab-1/ GM-Tg-hg-SE0706-Ab-2; GM-Tg-rg-SE0706-Ab-1/ GM-Tg-rg-SE0706-Ab-2; GM-Tg-mg-SE0706-Ab-1/ GM-Tg-mg-SE0706-Ab-2; GM-Tg-cynog-SE0706-Ab-1/ GM-Tg-cynog-SE0706-Ab-2; GM-Tg-felg-SE0706-Ab-1/ GM-Tg-felg-SE0706-Ab-2; GM-Tg-cang-SE0706-Ab-1/ GM-Tg-cang-SE0706-Ab-2; GM-Tg-bovg-SE0706-Ab-1/ GM-Tg-bovg-SE0706-Ab-2; GM-Tg-equg-SE0706-Ab-1/ GM-Tg-equg-SE0706-Ab-2 |
| Products Name | Anti-C1QA monoclonal antibody |
| Format | mab |
| Target Name | C1QA |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-C1QA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0706-Ag-1 | Recombinant multi-species C1QA protein |
| ORF Viral Vector | pGMLP002262 | human C1QA Lentivirus plasmid |
| ORF Viral Vector | vGMLP002262 | human C1QA Lentivirus particle |
| ORF Viral Vector | pGMLPm002257 | mouse C1qa Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002257 | mouse C1qa Lentivirus particle |
Target information
| Target ID | GM-SE0706 |
| Target Name | C1QA |
| Gene ID | 712,12259,298566,708477,478194,101096082,534961,100058097 |
| Gene Symbol and Synonyms | Adic,C1q,C1QA,C1QD1 |
| Uniprot Accession | P02745,P31720,Q5E9E3 |
| Uniprot Entry Name | C1QA_HUMAN,C1QA_RAT,C1QA_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000173372 |
| Target Classification | N/A |
The target: C1QA, gene name: C1QA, also named as . This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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