Anti-C1QT3/ C1QTNF3/ C1ATNF3 functional antibody
Anti-C1QT3/ C1QTNF3/ C1ATNF3 functional antibody for cell culture, ELISA & in-vivo assay
Go to C1QTNF3/C1QTNF3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0713-Ab-1/ GM-Tg-hg-SE0713-Ab-2 | Anti-Human C1QTNF3 monoclonal antibody | Human |
GM-Tg-rg-SE0713-Ab-1/ GM-Tg-rg-SE0713-Ab-2 | Anti-Rat C1QTNF3 monoclonal antibody | Rat |
GM-Tg-mg-SE0713-Ab-1/ GM-Tg-mg-SE0713-Ab-2 | Anti-Mouse C1QTNF3 monoclonal antibody | Mouse |
GM-Tg-cynog-SE0713-Ab-1/ GM-Tg-cynog-SE0713-Ab-2 | Anti-Cynomolgus/ Rhesus macaque C1QTNF3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0713-Ab-1/ GM-Tg-felg-SE0713-Ab-2 | Anti-Feline C1QTNF3 monoclonal antibody | Feline |
GM-Tg-cang-SE0713-Ab-1/ GM-Tg-cang-SE0713-Ab-2 | Anti-Canine C1QTNF3 monoclonal antibody | Canine |
GM-Tg-bovg-SE0713-Ab-1/ GM-Tg-bovg-SE0713-Ab-2 | Anti-Bovine C1QTNF3 monoclonal antibody | Bovine |
GM-Tg-equg-SE0713-Ab-1/ GM-Tg-equg-SE0713-Ab-2 | Anti-Equine C1QTNF3 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE0713-Ab-1/ GM-Tg-hg-SE0713-Ab-2; GM-Tg-rg-SE0713-Ab-1/ GM-Tg-rg-SE0713-Ab-2; GM-Tg-mg-SE0713-Ab-1/ GM-Tg-mg-SE0713-Ab-2; GM-Tg-cynog-SE0713-Ab-1/ GM-Tg-cynog-SE0713-Ab-2; GM-Tg-felg-SE0713-Ab-1/ GM-Tg-felg-SE0713-Ab-2; GM-Tg-cang-SE0713-Ab-1/ GM-Tg-cang-SE0713-Ab-2; GM-Tg-bovg-SE0713-Ab-1/ GM-Tg-bovg-SE0713-Ab-2; GM-Tg-equg-SE0713-Ab-1/ GM-Tg-equg-SE0713-Ab-2 |
Products Name | Anti-C1QTNF3 monoclonal antibody |
Format | mab |
Target Name | C1QTNF3 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-C1QTNF3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE0713-Ag-1 | Recombinant multi-species C1QT3/ C1QTNF3/ C1ATNF3 protein |
ORF Viral Vector | pGMLP001918 | human C1QTNF3 Lentivirus plasmid |
ORF Viral Vector | vGMLP001918 | human C1QTNF3 Lentivirus particle |
ORF Viral Vector | pGMAAV000238 | Norway rat C1qtnf3 AAV plasmid |
ORF Viral Vector | pGMLPm003695 | mouse C1qtnf3 Lentivirus plasmid |
ORF Viral Vector | vGMAAV000238 | Norway rat C1qtnf3 AAV particle |
ORF Viral Vector | vGMLPm003695 | mouse C1qtnf3 Lentivirus particle |
Target information
Target ID | GM-SE0713 |
Target Name | C1QTNF3 |
Gene ID | 114899,81799,294806,702339,610959,101081444,531659,100054043 |
Gene Symbol and Synonyms | 2310005P21Rik,Adim,C1ATNF3,C1QTNF3,CORCS,CORS,CORS-26,CORS26,CTRP3 |
Uniprot Accession | Q9BXJ4 |
Uniprot Entry Name | C1QT3_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000082196 |
Target Classification | N/A |
The target: C1QTNF3, gene name: C1QTNF3, also named as C1ATNF3, CORCS, CORS, CORS-26, CORS26, CTRP3. Enables identical protein binding activity. Involved in several processes, including cellular triglyceride homeostasis; negative regulation of NIK/NF-kappaB signaling; and regulation of cytokine production. Acts upstream of or within negative regulation of gluconeogenesis. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.