Anti-C1RL/ C1RL1P/ C1r-LP functional antibody

Anti-C1RL/ C1RL1P/ C1r-LP functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to C1RL/C1RL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0719-Ab-1/ GM-Tg-hg-SE0719-Ab-2Anti-Human C1RL monoclonal antibodyHuman
GM-Tg-rg-SE0719-Ab-1/ GM-Tg-rg-SE0719-Ab-2Anti-Rat C1RL monoclonal antibodyRat
GM-Tg-mg-SE0719-Ab-1/ GM-Tg-mg-SE0719-Ab-2Anti-Mouse C1RL monoclonal antibodyMouse
GM-Tg-cynog-SE0719-Ab-1/ GM-Tg-cynog-SE0719-Ab-2Anti-Cynomolgus/ Rhesus macaque C1RL monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0719-Ab-1/ GM-Tg-felg-SE0719-Ab-2Anti-Feline C1RL monoclonal antibodyFeline
GM-Tg-cang-SE0719-Ab-1/ GM-Tg-cang-SE0719-Ab-2Anti-Canine C1RL monoclonal antibodyCanine
GM-Tg-bovg-SE0719-Ab-1/ GM-Tg-bovg-SE0719-Ab-2Anti-Bovine C1RL monoclonal antibodyBovine
GM-Tg-equg-SE0719-Ab-1/ GM-Tg-equg-SE0719-Ab-2Anti-Equine C1RL monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0719-Ab-1/ GM-Tg-hg-SE0719-Ab-2; GM-Tg-rg-SE0719-Ab-1/ GM-Tg-rg-SE0719-Ab-2;
GM-Tg-mg-SE0719-Ab-1/ GM-Tg-mg-SE0719-Ab-2; GM-Tg-cynog-SE0719-Ab-1/ GM-Tg-cynog-SE0719-Ab-2;
GM-Tg-felg-SE0719-Ab-1/ GM-Tg-felg-SE0719-Ab-2; GM-Tg-cang-SE0719-Ab-1/ GM-Tg-cang-SE0719-Ab-2;
GM-Tg-bovg-SE0719-Ab-1/ GM-Tg-bovg-SE0719-Ab-2; GM-Tg-equg-SE0719-Ab-1/ GM-Tg-equg-SE0719-Ab-2
Products NameAnti-C1RL monoclonal antibody
Formatmab
Target NameC1RL
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-C1RL benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0719-Ag-1Recombinant multi-species C1RL/ C1RL1P/ C1r-LP protein


    Target information

    Target IDGM-SE0719
    Target NameC1RL
    Gene ID51279,232371,408246,486713,101094109,507633,100060326
    Gene Symbol and SynonymsC1r-LP,C1RL,C1RL1,C1RLP,CLSPa
    Uniprot AccessionQ9NZP8,Q6IE64
    Uniprot Entry NameC1RL_HUMAN,C1RL_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139178
    Target ClassificationN/A

    The target: C1RL, gene name: C1RL, also named as C1RL1P, C1r-LP, CLSPa, C1RL. Predicted to enable serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.