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Anti-IF/ CBLIF/ GIF functional antibody
Anti-IF/ CBLIF/ GIF functional antibody for cell culture, ELISA & in-vivo assay
Go to CBLIF/CBLIF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0730-Ab-1/ GM-Tg-hg-SE0730-Ab-2 | Anti-Human CBLIF monoclonal antibody | Human |
| GM-Tg-rg-SE0730-Ab-1/ GM-Tg-rg-SE0730-Ab-2 | Anti-Rat CBLIF monoclonal antibody | Rat |
| GM-Tg-mg-SE0730-Ab-1/ GM-Tg-mg-SE0730-Ab-2 | Anti-Mouse CBLIF monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0730-Ab-1/ GM-Tg-cynog-SE0730-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CBLIF monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0730-Ab-1/ GM-Tg-felg-SE0730-Ab-2 | Anti-Feline CBLIF monoclonal antibody | Feline |
| GM-Tg-cang-SE0730-Ab-1/ GM-Tg-cang-SE0730-Ab-2 | Anti-Canine CBLIF monoclonal antibody | Canine |
| GM-Tg-bovg-SE0730-Ab-1/ GM-Tg-bovg-SE0730-Ab-2 | Anti-Bovine CBLIF monoclonal antibody | Bovine |
| GM-Tg-equg-SE0730-Ab-1/ GM-Tg-equg-SE0730-Ab-2 | Anti-Equine CBLIF monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0730-Ab-1/ GM-Tg-hg-SE0730-Ab-2; GM-Tg-rg-SE0730-Ab-1/ GM-Tg-rg-SE0730-Ab-2; GM-Tg-mg-SE0730-Ab-1/ GM-Tg-mg-SE0730-Ab-2; GM-Tg-cynog-SE0730-Ab-1/ GM-Tg-cynog-SE0730-Ab-2; GM-Tg-felg-SE0730-Ab-1/ GM-Tg-felg-SE0730-Ab-2; GM-Tg-cang-SE0730-Ab-1/ GM-Tg-cang-SE0730-Ab-2; GM-Tg-bovg-SE0730-Ab-1/ GM-Tg-bovg-SE0730-Ab-2; GM-Tg-equg-SE0730-Ab-1/ GM-Tg-equg-SE0730-Ab-2 |
| Products Name | Anti-CBLIF monoclonal antibody |
| Format | mab |
| Target Name | CBLIF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CBLIF benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0730-Ag-1 | Recombinant multi-species IF/ CBLIF/ GIF protein |
| ORF Viral Vector | vGMLP003781 | human GIF Lentivirus particle |
| ORF Viral Vector | pGMLP003781 | human GIF Lentivirus plasmid |
Target information
| Target ID | GM-SE0730 |
| Target Name | CBLIF |
| Gene ID | 2694,29319,698704,449477,101101254,616252,100060988 |
| Gene Symbol and Synonyms | CBLIF,GIF,IF,IFMH,INF,TCN3 |
| Uniprot Accession | P27352,P17267,Q5XWD5 |
| Uniprot Entry Name | IF_HUMAN,IF_RAT,IF_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000134812 |
| Target Classification | N/A |
The target: CBLIF, gene name: CBLIF, also named as GIF, IF, IFMH, INF, TCN3. This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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