Anti-CBLN2 functional antibody

Anti-CBLN2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CBLN2/CBLN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0732-Ab-1/ GM-Tg-hg-SE0732-Ab-2Anti-Human CBLN2 monoclonal antibodyHuman
GM-Tg-rg-SE0732-Ab-1/ GM-Tg-rg-SE0732-Ab-2Anti-Rat CBLN2 monoclonal antibodyRat
GM-Tg-mg-SE0732-Ab-1/ GM-Tg-mg-SE0732-Ab-2Anti-Mouse CBLN2 monoclonal antibodyMouse
GM-Tg-cynog-SE0732-Ab-1/ GM-Tg-cynog-SE0732-Ab-2Anti-Cynomolgus/ Rhesus macaque CBLN2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0732-Ab-1/ GM-Tg-felg-SE0732-Ab-2Anti-Feline CBLN2 monoclonal antibodyFeline
GM-Tg-cang-SE0732-Ab-1/ GM-Tg-cang-SE0732-Ab-2Anti-Canine CBLN2 monoclonal antibodyCanine
GM-Tg-bovg-SE0732-Ab-1/ GM-Tg-bovg-SE0732-Ab-2Anti-Bovine CBLN2 monoclonal antibodyBovine
GM-Tg-equg-SE0732-Ab-1/ GM-Tg-equg-SE0732-Ab-2Anti-Equine CBLN2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0732-Ab-1/ GM-Tg-hg-SE0732-Ab-2; GM-Tg-rg-SE0732-Ab-1/ GM-Tg-rg-SE0732-Ab-2;
GM-Tg-mg-SE0732-Ab-1/ GM-Tg-mg-SE0732-Ab-2; GM-Tg-cynog-SE0732-Ab-1/ GM-Tg-cynog-SE0732-Ab-2;
GM-Tg-felg-SE0732-Ab-1/ GM-Tg-felg-SE0732-Ab-2; GM-Tg-cang-SE0732-Ab-1/ GM-Tg-cang-SE0732-Ab-2;
GM-Tg-bovg-SE0732-Ab-1/ GM-Tg-bovg-SE0732-Ab-2; GM-Tg-equg-SE0732-Ab-1/ GM-Tg-equg-SE0732-Ab-2
Products NameAnti-CBLN2 monoclonal antibody
Formatmab
Target NameCBLN2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CBLN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0732-Ag-1Recombinant multi-species CBLN2 protein


    Target information

    Target IDGM-SE0732
    Target NameCBLN2
    Gene ID147381,12405,291388,694193,483936,101098260,509847,106780950
    Gene Symbol and Synonyms6330593N19Rik,A730004O05,CBLN2
    Uniprot AccessionQ8IUK8,P98087
    Uniprot Entry NameCBLN2_HUMAN,CBLN2_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000141668
    Target ClassificationN/A

    The target: CBLN2, gene name: CBLN2, also named as . Predicted to be involved in maintenance of synapse structure and spontaneous synaptic transmission. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in extracellular space. Predicted to be active in glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.