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Anti-CCL3L3/464.2/ D17S1718 functional antibody
Anti-CCL3L3/464.2/ D17S1718 functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL3L3/CCL3L3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0749-Ab-1/ GM-Tg-hg-SE0749-Ab-2 | Anti-Human CCL3L3 monoclonal antibody | Human |
| GM-Tg-rg-SE0749-Ab-1/ GM-Tg-rg-SE0749-Ab-2 | Anti-Rat CCL3L3 monoclonal antibody | Rat |
| GM-Tg-mg-SE0749-Ab-1/ GM-Tg-mg-SE0749-Ab-2 | Anti-Mouse CCL3L3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0749-Ab-1/ GM-Tg-cynog-SE0749-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL3L3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0749-Ab-1/ GM-Tg-felg-SE0749-Ab-2 | Anti-Feline CCL3L3 monoclonal antibody | Feline |
| GM-Tg-cang-SE0749-Ab-1/ GM-Tg-cang-SE0749-Ab-2 | Anti-Canine CCL3L3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0749-Ab-1/ GM-Tg-bovg-SE0749-Ab-2 | Anti-Bovine CCL3L3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0749-Ab-1/ GM-Tg-equg-SE0749-Ab-2 | Anti-Equine CCL3L3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0749-Ab-1/ GM-Tg-hg-SE0749-Ab-2; GM-Tg-rg-SE0749-Ab-1/ GM-Tg-rg-SE0749-Ab-2; GM-Tg-mg-SE0749-Ab-1/ GM-Tg-mg-SE0749-Ab-2; GM-Tg-cynog-SE0749-Ab-1/ GM-Tg-cynog-SE0749-Ab-2; GM-Tg-felg-SE0749-Ab-1/ GM-Tg-felg-SE0749-Ab-2; GM-Tg-cang-SE0749-Ab-1/ GM-Tg-cang-SE0749-Ab-2; GM-Tg-bovg-SE0749-Ab-1/ GM-Tg-bovg-SE0749-Ab-2; GM-Tg-equg-SE0749-Ab-1/ GM-Tg-equg-SE0749-Ab-2 |
| Products Name | Anti-CCL3L3 monoclonal antibody |
| Format | mab |
| Target Name | CCL3L3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL3L3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0749-Ag-1 | Recombinant multi-species CCL3L3/464.2/ D17S1718 protein |
Target information
| Target ID | GM-SE0749 |
| Target Name | CCL3L3 |
| Gene ID | 414062 |
| Gene Symbol and Synonyms | 464.2,CCL3L3,D17S1718,G0S19-2,LD78,LD78BETA,SCYA3L,SCYA3L1 |
| Uniprot Accession | N/A |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000276085 |
| Target Classification | N/A |
The target: CCL3L3, gene name: CCL3L3, also named as 464.2, D17S1718, G0S19-2, LD78, LD78BETA, SCYA3L, SCYA3L1. This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility.[provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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