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Anti-CCL4L2/ AT744.2/ CCL4L functional antibody
Anti-CCL4L2/ AT744.2/ CCL4L functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL4L2/CCL4L2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0750-Ab-1/ GM-Tg-hg-SE0750-Ab-2 | Anti-Human CCL4L2 monoclonal antibody | Human |
| GM-Tg-rg-SE0750-Ab-1/ GM-Tg-rg-SE0750-Ab-2 | Anti-Rat CCL4L2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0750-Ab-1/ GM-Tg-mg-SE0750-Ab-2 | Anti-Mouse CCL4L2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0750-Ab-1/ GM-Tg-cynog-SE0750-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL4L2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0750-Ab-1/ GM-Tg-felg-SE0750-Ab-2 | Anti-Feline CCL4L2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0750-Ab-1/ GM-Tg-cang-SE0750-Ab-2 | Anti-Canine CCL4L2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0750-Ab-1/ GM-Tg-bovg-SE0750-Ab-2 | Anti-Bovine CCL4L2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0750-Ab-1/ GM-Tg-equg-SE0750-Ab-2 | Anti-Equine CCL4L2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0750-Ab-1/ GM-Tg-hg-SE0750-Ab-2; GM-Tg-rg-SE0750-Ab-1/ GM-Tg-rg-SE0750-Ab-2; GM-Tg-mg-SE0750-Ab-1/ GM-Tg-mg-SE0750-Ab-2; GM-Tg-cynog-SE0750-Ab-1/ GM-Tg-cynog-SE0750-Ab-2; GM-Tg-felg-SE0750-Ab-1/ GM-Tg-felg-SE0750-Ab-2; GM-Tg-cang-SE0750-Ab-1/ GM-Tg-cang-SE0750-Ab-2; GM-Tg-bovg-SE0750-Ab-1/ GM-Tg-bovg-SE0750-Ab-2; GM-Tg-equg-SE0750-Ab-1/ GM-Tg-equg-SE0750-Ab-2 |
| Products Name | Anti-CCL4L2 monoclonal antibody |
| Format | mab |
| Target Name | CCL4L2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL4L2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0750-Ag-1 | Recombinant multi-species CCL4L2/ AT744.2/ CCL4L protein |
Target information
| Target ID | GM-SE0750 |
| Target Name | CCL4L2 |
| Gene ID | 9560 |
| Gene Symbol and Synonyms | AT744.2,CCL4L,CCL4L2,SCYA4L,SCYQ4L2 |
| Uniprot Accession | N/A |
| Uniprot Entry Name | |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000276070 |
| Target Classification | N/A |
The target: CCL4L2, gene name: CCL4L2, also named as AT744.2, CCL4L, SCYA4L, SCYQ4L2. This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. This gene copy contains a non-consensus splice acceptor site at the 3' terminal exon found in other highly similar gene copies, and it thus uses other alternative splice sites for the 3' terminal exon, resulting in multiple transcript variants. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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