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Anti-CGB1 functional antibody
Anti-CGB1 functional antibody for cell culture, ELISA & in-vivo assay
Go to CGB1/CGB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0767-Ab-1/ GM-Tg-hg-SE0767-Ab-2 | Anti-Human CGB1 monoclonal antibody | Human |
| GM-Tg-rg-SE0767-Ab-1/ GM-Tg-rg-SE0767-Ab-2 | Anti-Rat CGB1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0767-Ab-1/ GM-Tg-mg-SE0767-Ab-2 | Anti-Mouse CGB1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0767-Ab-1/ GM-Tg-cynog-SE0767-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CGB1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0767-Ab-1/ GM-Tg-felg-SE0767-Ab-2 | Anti-Feline CGB1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0767-Ab-1/ GM-Tg-cang-SE0767-Ab-2 | Anti-Canine CGB1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0767-Ab-1/ GM-Tg-bovg-SE0767-Ab-2 | Anti-Bovine CGB1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0767-Ab-1/ GM-Tg-equg-SE0767-Ab-2 | Anti-Equine CGB1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0767-Ab-1/ GM-Tg-hg-SE0767-Ab-2; GM-Tg-rg-SE0767-Ab-1/ GM-Tg-rg-SE0767-Ab-2; GM-Tg-mg-SE0767-Ab-1/ GM-Tg-mg-SE0767-Ab-2; GM-Tg-cynog-SE0767-Ab-1/ GM-Tg-cynog-SE0767-Ab-2; GM-Tg-felg-SE0767-Ab-1/ GM-Tg-felg-SE0767-Ab-2; GM-Tg-cang-SE0767-Ab-1/ GM-Tg-cang-SE0767-Ab-2; GM-Tg-bovg-SE0767-Ab-1/ GM-Tg-bovg-SE0767-Ab-2; GM-Tg-equg-SE0767-Ab-1/ GM-Tg-equg-SE0767-Ab-2 |
| Products Name | Anti-CGB1 monoclonal antibody |
| Format | mab |
| Target Name | CGB1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CGB1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0767-Ag-1 | Recombinant multi-species CGB1 protein |
Target information
| Target ID | GM-SE0767 |
| Target Name | CGB1 |
| Gene ID | 114335 |
| Gene Symbol and Synonyms | CGB1 |
| Uniprot Accession | A6NKQ9 |
| Uniprot Entry Name | CGB1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000267631 |
| Target Classification | N/A |
The target: CGB1, gene name: CGB1, also named as . The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB1 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017). However, a 155 aa protein, translated from a different frame, is about the same size, and shares 98% identity with other CGB subunits. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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