Anti-CGB8 functional antibody

Anti-CGB8 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CGB8/CGB8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0771-Ab-1/ GM-Tg-hg-SE0771-Ab-2Anti-Human CGB8 monoclonal antibodyHuman
GM-Tg-rg-SE0771-Ab-1/ GM-Tg-rg-SE0771-Ab-2Anti-Rat CGB8 monoclonal antibodyRat
GM-Tg-mg-SE0771-Ab-1/ GM-Tg-mg-SE0771-Ab-2Anti-Mouse CGB8 monoclonal antibodyMouse
GM-Tg-cynog-SE0771-Ab-1/ GM-Tg-cynog-SE0771-Ab-2Anti-Cynomolgus/ Rhesus macaque CGB8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0771-Ab-1/ GM-Tg-felg-SE0771-Ab-2Anti-Feline CGB8 monoclonal antibodyFeline
GM-Tg-cang-SE0771-Ab-1/ GM-Tg-cang-SE0771-Ab-2Anti-Canine CGB8 monoclonal antibodyCanine
GM-Tg-bovg-SE0771-Ab-1/ GM-Tg-bovg-SE0771-Ab-2Anti-Bovine CGB8 monoclonal antibodyBovine
GM-Tg-equg-SE0771-Ab-1/ GM-Tg-equg-SE0771-Ab-2Anti-Equine CGB8 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0771-Ab-1/ GM-Tg-hg-SE0771-Ab-2; GM-Tg-rg-SE0771-Ab-1/ GM-Tg-rg-SE0771-Ab-2;
GM-Tg-mg-SE0771-Ab-1/ GM-Tg-mg-SE0771-Ab-2; GM-Tg-cynog-SE0771-Ab-1/ GM-Tg-cynog-SE0771-Ab-2;
GM-Tg-felg-SE0771-Ab-1/ GM-Tg-felg-SE0771-Ab-2; GM-Tg-cang-SE0771-Ab-1/ GM-Tg-cang-SE0771-Ab-2;
GM-Tg-bovg-SE0771-Ab-1/ GM-Tg-bovg-SE0771-Ab-2; GM-Tg-equg-SE0771-Ab-1/ GM-Tg-equg-SE0771-Ab-2
Products NameAnti-CGB8 monoclonal antibody
Formatmab
Target NameCGB8
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CGB8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0771-Ag-1Recombinant multi-species CGB8 protein


    Target information

    Target IDGM-SE0771
    Target NameCGB8
    Gene ID94115
    Gene Symbol and SynonymsCGB8
    Uniprot AccessionN/A
    Uniprot Entry Name
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000213030
    Target ClassificationN/A

    The target: CGB8, gene name: CGB8, also named as . This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 8 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.