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Anti-CH3L1/ CHI3L1/ ASRT7 functional antibody
Anti-CH3L1/ CHI3L1/ ASRT7 functional antibody for cell culture, ELISA & in-vivo assay
Go to CHI3L1/CHI3L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0775-Ab-1/ GM-Tg-hg-SE0775-Ab-2 | Anti-Human CHI3L1 monoclonal antibody | Human |
| GM-Tg-rg-SE0775-Ab-1/ GM-Tg-rg-SE0775-Ab-2 | Anti-Rat CHI3L1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0775-Ab-1/ GM-Tg-mg-SE0775-Ab-2 | Anti-Mouse CHI3L1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0775-Ab-1/ GM-Tg-cynog-SE0775-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CHI3L1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0775-Ab-1/ GM-Tg-felg-SE0775-Ab-2 | Anti-Feline CHI3L1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0775-Ab-1/ GM-Tg-cang-SE0775-Ab-2 | Anti-Canine CHI3L1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0775-Ab-1/ GM-Tg-bovg-SE0775-Ab-2 | Anti-Bovine CHI3L1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0775-Ab-1/ GM-Tg-equg-SE0775-Ab-2 | Anti-Equine CHI3L1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0775-Ab-1/ GM-Tg-hg-SE0775-Ab-2; GM-Tg-rg-SE0775-Ab-1/ GM-Tg-rg-SE0775-Ab-2; GM-Tg-mg-SE0775-Ab-1/ GM-Tg-mg-SE0775-Ab-2; GM-Tg-cynog-SE0775-Ab-1/ GM-Tg-cynog-SE0775-Ab-2; GM-Tg-felg-SE0775-Ab-1/ GM-Tg-felg-SE0775-Ab-2; GM-Tg-cang-SE0775-Ab-1/ GM-Tg-cang-SE0775-Ab-2; GM-Tg-bovg-SE0775-Ab-1/ GM-Tg-bovg-SE0775-Ab-2; GM-Tg-equg-SE0775-Ab-1/ GM-Tg-equg-SE0775-Ab-2 |
| Products Name | Anti-CHI3L1 monoclonal antibody |
| Format | mab |
| Target Name | CHI3L1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CHI3L1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0775-Ag-1 | Recombinant multi-species CH3L1/ CHI3L1/ ASRT7 protein |
| ORF Viral Vector | pGMLP001925 | human CHI3L1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001925 | human CHI3L1 Lentivirus particle |
| ORF Viral Vector | pGMLV000663 | Norway rat CHI3L1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000663 | Norway rat CHI3L1 Lentivirus particle |
| ORF Viral Vector | pGMLPm001986 | mouse Chil1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001986 | mouse Chil1 Lentivirus particle |
Target information
| Target ID | GM-SE0775 |
| Target Name | CHI3L1 |
| Gene ID | 1116,12654,89824,703401,490222,101100781,286869,100052556 |
| Gene Symbol and Synonyms | ASRT7,Brp39,CGP-39,CHI3L1,Chil1,CLP-1,GP-39,GP39,HC-gp39,hCGP-39,HCGP-3P,SPC-40,SPS-40,YK-40,YKL-40,YKL40,YYL-40 |
| Uniprot Accession | P36222,Q9WTV1,P30922 |
| Uniprot Entry Name | CH3L1_HUMAN,CH3L1_RAT,CH3L1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | Ovary Cancer, Acute kidney failure |
| Gene Ensembl | ENSG00000133048 |
| Target Classification | N/A |
The target: CHI3L1, gene name: CHI3L1, also named as ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YK-40, YKL-40, YKL40, YYL-40, hCGP-39. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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