Anti-CL19A/ CLEC19A functional antibody

Anti-CL19A/ CLEC19A functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CLEC19A/CLEC19A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0785-Ab-1/ GM-Tg-hg-SE0785-Ab-2Anti-Human CLEC19A monoclonal antibodyHuman
GM-Tg-rg-SE0785-Ab-1/ GM-Tg-rg-SE0785-Ab-2Anti-Rat CLEC19A monoclonal antibodyRat
GM-Tg-mg-SE0785-Ab-1/ GM-Tg-mg-SE0785-Ab-2Anti-Mouse CLEC19A monoclonal antibodyMouse
GM-Tg-cynog-SE0785-Ab-1/ GM-Tg-cynog-SE0785-Ab-2Anti-Cynomolgus/ Rhesus macaque CLEC19A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0785-Ab-1/ GM-Tg-felg-SE0785-Ab-2Anti-Feline CLEC19A monoclonal antibodyFeline
GM-Tg-cang-SE0785-Ab-1/ GM-Tg-cang-SE0785-Ab-2Anti-Canine CLEC19A monoclonal antibodyCanine
GM-Tg-bovg-SE0785-Ab-1/ GM-Tg-bovg-SE0785-Ab-2Anti-Bovine CLEC19A monoclonal antibodyBovine
GM-Tg-equg-SE0785-Ab-1/ GM-Tg-equg-SE0785-Ab-2Anti-Equine CLEC19A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0785-Ab-1/ GM-Tg-hg-SE0785-Ab-2; GM-Tg-rg-SE0785-Ab-1/ GM-Tg-rg-SE0785-Ab-2;
GM-Tg-mg-SE0785-Ab-1/ GM-Tg-mg-SE0785-Ab-2; GM-Tg-cynog-SE0785-Ab-1/ GM-Tg-cynog-SE0785-Ab-2;
GM-Tg-felg-SE0785-Ab-1/ GM-Tg-felg-SE0785-Ab-2; GM-Tg-cang-SE0785-Ab-1/ GM-Tg-cang-SE0785-Ab-2;
GM-Tg-bovg-SE0785-Ab-1/ GM-Tg-bovg-SE0785-Ab-2; GM-Tg-equg-SE0785-Ab-1/ GM-Tg-equg-SE0785-Ab-2
Products NameAnti-CLEC19A monoclonal antibody
Formatmab
Target NameCLEC19A
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CLEC19A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0785-Ag-1Recombinant multi-species CL19A/ CLEC19A protein


    Target information

    Target IDGM-SE0785
    Target NameCLEC19A
    Gene ID728276,100909498,694333,479830,109495261,100139157,100052906
    Gene Symbol and SynonymsCLEC19A
    Uniprot AccessionQ6UXS0
    Uniprot Entry NameCL19A_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000261210
    Target ClassificationN/A

    The target: CLEC19A, gene name: CLEC19A, also named as . Predicted to enable carbohydrate binding activity. Predicted to be located in extracellular region. .



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.