Anti-CNDP1/ CN1/ CPGL2 functional antibody

Anti-CNDP1/ CN1/ CPGL2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to CNDP1/CNDP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0789-Ab-1/ GM-Tg-hg-SE0789-Ab-2Anti-Human CNDP1 monoclonal antibodyHuman
GM-Tg-rg-SE0789-Ab-1/ GM-Tg-rg-SE0789-Ab-2Anti-Rat CNDP1 monoclonal antibodyRat
GM-Tg-mg-SE0789-Ab-1/ GM-Tg-mg-SE0789-Ab-2Anti-Mouse CNDP1 monoclonal antibodyMouse
GM-Tg-cynog-SE0789-Ab-1/ GM-Tg-cynog-SE0789-Ab-2Anti-Cynomolgus/ Rhesus macaque CNDP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0789-Ab-1/ GM-Tg-felg-SE0789-Ab-2Anti-Feline CNDP1 monoclonal antibodyFeline
GM-Tg-cang-SE0789-Ab-1/ GM-Tg-cang-SE0789-Ab-2Anti-Canine CNDP1 monoclonal antibodyCanine
GM-Tg-bovg-SE0789-Ab-1/ GM-Tg-bovg-SE0789-Ab-2Anti-Bovine CNDP1 monoclonal antibodyBovine
GM-Tg-equg-SE0789-Ab-1/ GM-Tg-equg-SE0789-Ab-2Anti-Equine CNDP1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0789-Ab-1/ GM-Tg-hg-SE0789-Ab-2; GM-Tg-rg-SE0789-Ab-1/ GM-Tg-rg-SE0789-Ab-2;
GM-Tg-mg-SE0789-Ab-1/ GM-Tg-mg-SE0789-Ab-2; GM-Tg-cynog-SE0789-Ab-1/ GM-Tg-cynog-SE0789-Ab-2;
GM-Tg-felg-SE0789-Ab-1/ GM-Tg-felg-SE0789-Ab-2; GM-Tg-cang-SE0789-Ab-1/ GM-Tg-cang-SE0789-Ab-2;
GM-Tg-bovg-SE0789-Ab-1/ GM-Tg-bovg-SE0789-Ab-2; GM-Tg-equg-SE0789-Ab-1/ GM-Tg-equg-SE0789-Ab-2
Products NameAnti-CNDP1 monoclonal antibody
Formatmab
Target NameCNDP1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CNDP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0789-Ag-1Recombinant multi-species CNDP1/ CN1/ CPGL2 protein
    ORF Viral VectorvGMLV000584human CNDP1 Lentivirus particle
    ORF Viral VectorpGMLV000584human CNDP1 Lentivirus plasmid


    Target information

    Target IDGM-SE0789
    Target NameCNDP1
    Gene ID84735,338403,307212,695195,476165,101099503,614200,100061728
    Gene Symbol and SynonymsCN1,CNDP1,CPGL2,HsT2308
    Uniprot AccessionQ96KN2,Q66HG3
    Uniprot Entry NameCNDP1_HUMAN,CNDP1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000150656
    Target ClassificationN/A

    The target: CNDP1, gene name: CNDP1, also named as CN1, CPGL2, HsT2308. This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.